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Found 972 with Last Name = 'liu' and Initial = 'bf'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208446(CHEMBL3884161)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208470(CHEMBL3885003)
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM194780(7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butox...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H](+)8-OH-DPAT from human 5HT1A receptor expressed in human HeLa cells measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]-ketanserine from serotonin 5-HT2A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208451(CHEMBL3885471)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in Sprague-Dawley rat striatum incubated for 30 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50001043(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membrane incubated for 2.5 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50581486(CHEMBL5082165)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H]DAMGO from MOR in Sprague-Dawley rat brain membranes measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50434823(CHEMBL2387229)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM194780(7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butox...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]raclopride from human D2 long receptor expressed in CHO cells measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208447(CHEMBL3883955)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208447(CHEMBL3883955)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50008984(4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-ph...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208441(CHEMBL3885254)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208441(CHEMBL3885254)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in Sprague-Dawley rat striatum incubated for 30 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469526(CHEMBL4290311)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-ketanserine from serotonin 5-HT2A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM194780(7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butox...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO-K1 cells measured after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208447(CHEMBL3883955)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5-HT6 receptor expressed in CHO cell membranes for 30 mins by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208451(CHEMBL3885471)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208447(CHEMBL3883955)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in Sprague-Dawley rat striatum incubated for 30 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208442(CHEMBL3884733)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208447(CHEMBL3883955)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM423299(US10501452, Compound 5)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469497(CHEMBL4289498)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208446(CHEMBL3884161)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50009386(CHEMBL3233867)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]-ketanserin from rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]-ketanserine from serotonin 5-HT2A receptor in rat brain cortex homogenates incubated for 30 mins by liquid scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  0.720nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50009388(CHEMBL3233869)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]-ketanserin from rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50005708(CHEMBL3235459)
Affinity DataKi:  0.770nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50034089(CHEMBL3359238)
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in Dunkin Hartley guinea pig brain membranes after 180 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50208446(CHEMBL3884161)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat cerebral cortex incubated for 15 mins in presence of spiperone by liquid s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50581505(CHEMBL5094445)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Sprague-Dawley rat brain membranes measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50034088(CHEMBL3359237)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in Dunkin Hartley guinea pig brain membranes after 180 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50034090(CHEMBL3359239)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in Dunkin Hartley guinea pig brain membranes after 180 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50005672(CHEMBL3235447)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50005692(CHEMBL3235455)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50564197(CHEMBL4776178)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50170036(CHEMBL3805396)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from Sigma1 receptor in Dunkin Hartley guinea pig brain membrane after 180 mins by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50570443(CHEMBL4870716)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50005707(CHEMBL3235458)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50564176(CHEMBL4797982)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50564177(CHEMBL4778918)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-(+)-pnetazocin from sigma1 receptor in guinea pig brain membrane incubated for 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H] 7-OH-DPAT from dopamine D3 receptor in rat olfactory tubercle homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50469504(CHEMBL4293999)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to D3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50469497(CHEMBL4289498)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Jiangsu Ocean University

Curated by ChEMBL
LigandPNGBDBM50570453(CHEMBL4865907)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50005691(CHEMBL3235454)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in Dunkin Hartley guinea pig membrane after 180 mins by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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