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Found 251 with Last Name = 'loi' and Initial = 'ag'
TargetGenome polyprotein(Hepatitis C virus)
Idenix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50142916((1S,4R,6S,14S,18R)-14-Cyclopentyloxycarbonylamino-...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Idenix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50023510(CHEMBL3326826)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Idenix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50023579(CHEMBL3326830)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Idenix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50023508(CHEMBL3326539)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534627(CHEMBL4527971)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534648(CHEMBL4463284)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534659(CHEMBL4464159)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Idenix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50023578(CHEMBL3326829)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534649(CHEMBL4451988)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534627(CHEMBL4527971)
Affinity DataIC50:  9nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534646(CHEMBL4567705)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534629(CHEMBL4444480)
Affinity DataIC50:  14nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534647(CHEMBL4522572)
Affinity DataIC50:  16nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50:  16nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Idenix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50023509(CHEMBL3326540)
Affinity DataIC50:  17nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534650(CHEMBL4593826)
Affinity DataIC50:  18nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  18.5nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534635(CHEMBL4464724)
Affinity DataIC50:  21nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534629(CHEMBL4444480)
Affinity DataIC50:  24nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2278(3-(benzenesulfonyl)-5-chloro-1H-indole-2-carboxami...)
Affinity DataIC50:  25nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534652(CHEMBL4471005)
Affinity DataIC50:  25nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534655(CHEMBL4441399)
Affinity DataIC50:  26nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  26nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2482(5-Chloro-3-[(3,5-dimethylphenyl)sulfonyl]-1H-indol...)
Affinity DataIC50:  31nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  33nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534651(CHEMBL4548240)
Affinity DataIC50:  34nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  35nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2337(6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-...)
Affinity DataIC50:  40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus)
Idenix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50023507(CHEMBL3326538)
Affinity DataIC50:  45nMAssay Description:Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534645(CHEMBL4563132)
Affinity DataIC50:  46nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2334(6-[(2,6-difluorophenyl)methyl]-5-methyl-2-(propan-...)
Affinity DataIC50:  50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2335(2-(butan-2-ylsulfanyl)-6-[(2,6-difluorophenyl)meth...)
Affinity DataIC50:  50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2331(6-[(2,6-difluorophenyl)methyl]-2-(propan-2-ylsulfa...)
Affinity DataIC50:  50nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2399(Pyrrolyl Aryl Sulfone (PAS) 20 | ethyl 1-[(2-amino...)
Affinity DataIC50:  50nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2332(2-(butan-2-ylsulfanyl)-6-[(2,6-difluorophenyl)meth...)
Affinity DataIC50:  50nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534650(CHEMBL4593826)
Affinity DataIC50:  52nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534632(CHEMBL4578396)
Affinity DataIC50:  59nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2383(2-(butan-2-ylsulfanyl)-6-[(2,6-dichlorophenyl)meth...)
Affinity DataIC50:  60nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2392(2-(cyclohexylsulfanyl)-6-[(2,6-difluorophenyl)meth...)
Affinity DataIC50:  70nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2481(5-Chloro-3-[(4-methylphenyl)sulfonyl]-1H-indole-2-...)
Affinity DataIC50:  72nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50:  75nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2397(Ethyl 1-[(2-Amino-5-chlorophenyl)sulfonyl]-4-methy...)
Affinity DataIC50:  80nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2336(2-(cyclopentylsulfanyl)-6-[(2,6-difluorophenyl)met...)
Affinity DataIC50:  80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2333(2-(cyclopentylsulfanyl)-6-[(2,6-difluorophenyl)met...)
Affinity DataIC50:  80nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534637(CHEMBL4459000)
Affinity DataIC50:  81nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  85nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2388(2-(butylsulfanyl)-6-[(2,6-difluorophenyl)methyl]-5...)
Affinity DataIC50:  90nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2378(2-(cyclohexylsulfanyl)-6-[(2,6-difluorophenyl)meth...)
Affinity DataIC50:  90nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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