Found 212 with Last Name = 'loughran' and Initial = 'hm' 
Affinity DataIC50: 0.0120nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Val-Ser-Gln-Asn-(beta-naphtyl)Ala-Pro-Ile-Val as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0130nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Val-Ser-Gln-Asn-(beta-naphtyl)Ala-Pro-Ile-Val as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Val-Ser-Gln-Asn-(beta-naphtyl)Ala-Pro-Ile-Val as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro Oxytocin receptor antagonistic activity against rat uterine stripsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against bovine cathepsin DMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Choline AcetyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of Choline AcetyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory activity against aspartic proteinases pepsin from porcineMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:In vitro Oxytocin receptor antagonistic activity against rat uterine stripsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 338nMAssay Description:ETA receptor antagonist activity was measured by inhibition of ET-1 induced vasoconstriction in isolated porcine coronary arteryMore data for this Ligand-Target Pair
Affinity DataIC50: 585nMAssay Description:Inhibition of Choline AcetyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:In vitro Oxytocin receptor antagonistic activity against rat uterine stripsMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory potency against human kidney renin.More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+3nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase RNasH activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+3nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of Choline AcetyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Confirmatory Assay (CONFA) used as a secondary screen for confirming the mechanism of action of compounds identified as hits using the ALA assay. The...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.93E+3nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of Choline AcetyltransferaseMore data for this Ligand-Target Pair
