TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: 330nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: 520nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: 860nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: 1.65E+3nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: >2.90E+4nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
Affinity DataKi: >2.90E+4nMAssay Description:In vivo binding affinity for rat ventral prostate androgen receptor by displacement of [3H]R-1881More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human GRK2 by LANCE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18.5nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM threitolMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domainMore data for this Ligand-Target Pair
Affinity DataIC50: 34.3nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 36.2nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 36.7nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 42.1nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 44.3nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.01 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 47.6nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.1nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.25 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.3nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 1.00 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.7nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 48.9nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.05 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 52.5nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 53.1nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 53.4nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.10 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.05 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 56.5nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 10 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 56.7nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.10 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 60.4nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.25 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 65.2nMAssay Description:Inhibition of human carbonic anhydrase 9 in presence of 0.25 mM tris(carboxyethyl)phosphineMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.01 mM dithiothreitolMore data for this Ligand-Target Pair
Affinity DataIC50: 68.6nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.10 mM threitolMore data for this Ligand-Target Pair
Affinity DataIC50: 69.7nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 1.00 mM beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 77.8nMAssay Description:Inhibition of human carbonic anhydrase 2 in presence of 0.25 mM threitolMore data for this Ligand-Target Pair
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of human GRK2 by transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain in presence of 0.01 mM dithiothreitolMore data for this Ligand-Target Pair