Compile Data Set for Download or QSAR
maximum 50k data
Found 978 with Last Name = 'lyothier' and Initial = 'i'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  0.770nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639880(3-Ethoxy-5-{6-[2-(3-methoxy-1-methyl-naphthalen-2-...)
Affinity DataIC50:  1nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639881(5-{6-[2-(3-Cyano-1-methyl-naphthalen-2-yl)-ethylam...)
Affinity DataIC50:  1nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639887(3-Ethoxy-5-{6-[2-(6-methoxy-4-methyl-benzofuran-5-...)
Affinity DataIC50:  1nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640244(3-Ethoxy-5-{6-[2-(4-fluoro-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  1nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640273(2-Cyclobutoxy-4-{6-[2-(7-methoxy-5-methyl-2,3-dihy...)
Affinity DataIC50:  1nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640239(3-Ethoxy-5-{6-[2-(7-fluoro-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  1nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639918(3-Ethoxy-5-{6-[2-(7-ethoxy-2,3-dihydro-benzo[1,4]d...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640100(2-Ethoxy-4-{6-[2-(6-methoxy-4-methyl-benzofuran-5-...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640236(5-{6-[2-(7-Chloro-benzo[b]thiophen-5-yl)-ethylamin...)
Affinity DataIC50:  2nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639883(3-Ethoxy-5-{6-[2-(6-methoxy-benzo[b]thiophen-5-yl)...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640277(4-{6-[2-(7-Methoxy-5-methyl-2,3-dihydro-benzo[1,4]...)
Affinity DataIC50:  2nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639882(3-Ethoxy-5-{6-[2-(1-fluoro-3-methoxy-naphthalen-2-...)
Affinity DataIC50:  2nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639883(3-Ethoxy-5-{6-[2-(6-methoxy-benzo[b]thiophen-5-yl)...)
Affinity DataIC50:  3nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640213(5-{6-[2-(1,3-Difluoro-naphthalen-2-yl)-ethylamino]...)
Affinity DataIC50:  3nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639891(3-Ethoxy-5-{6-[2-(6-methoxy-benzofuran-5-yl)-ethyl...)
Affinity DataIC50:  3nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639884(5-[6-(2-Benzo[b]thiophen-5-yl-ethylamino)-pyrimidi...)
Affinity DataIC50:  3nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639885(5-{6-[2-(7-Cyano-2,3-dihydro-benzo[1,4]dioxin-6-yl...)
Affinity DataIC50:  4nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640016(4-{6-[2-(7-Ethoxy-2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50:  4nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639897(4-{6-[2-(6-Methoxy-benzo[b]thiophen-5-yl)-ethylami...)
Affinity DataIC50:  4nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640087(2-Cyclobutoxy-4-{6-[2-(6-methoxy-4-methyl-benzofur...)
Affinity DataIC50:  5nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640272(2-Ethoxy-4-{6-[2-(7-methoxy-5-methyl-2,3-dihydro-b...)
Affinity DataIC50:  5nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639886(3-Ethoxy-5-{6-[2-(1-methyl-naphthalen-2-yl)-ethyla...)
Affinity DataIC50:  5nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640300(3-(2-Ethoxy-4-{6-[2-(3-methoxy-1-methyl-naphthalen...)
Affinity DataIC50:  6nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639887(3-Ethoxy-5-{6-[2-(6-methoxy-4-methyl-benzofuran-5-...)
Affinity DataIC50:  6nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639888(3-Ethoxy-5-{6-[2-(3-methoxy-naphthalen-2-yl)-ethyl...)
Affinity DataIC50:  6nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639981((2-Ethoxy-4-{6-[2-(6-methoxy-4-methyl-benzofuran-5...)
Affinity DataIC50:  6nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640244(3-Ethoxy-5-{6-[2-(4-fluoro-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  6nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640268(3-Ethoxy-5-{6-[2-(7-methyl-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  6nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640005(2-Ethoxy-4-{6-[2-(6-ethoxy-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  6nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639889(5-[6-(2-Benzo[b]thiophen-6-yl-ethylamino)-pyrimidi...)
Affinity DataIC50:  6nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640282(4-{6-[2-(7-Fluoro-6-methoxy-benzo[b]thiophen-5-yl)...)
Affinity DataIC50:  7nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640305((4-{6-[2-(7-Methoxy-5-methyl-2,3-dihydro-benzo[1,4...)
Affinity DataIC50:  7nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639891(3-Ethoxy-5-{6-[2-(6-methoxy-benzofuran-5-yl)-ethyl...)
Affinity DataIC50:  7nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639890(3-Ethoxy-5-{6-[2-(1-fluoro-naphthalen-2-yl)-ethyla...)
Affinity DataIC50:  7nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639913(3-Ethoxy-5-{6-[2-(6-methyl-benzo[b]thiophen-5-yl)-...)
Affinity DataIC50:  8nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639928(3-Ethoxy-5-{6-[2-(6-methoxy-benzo[1,3]dioxol-5-yl)...)
Affinity DataIC50:  8nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639880(3-Ethoxy-5-{6-[2-(3-methoxy-1-methyl-naphthalen-2-...)
Affinity DataIC50:  8nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639892(3-Ethoxy-5-{6-[2-(6-fluoro-benzofuran-5-yl)-ethyla...)
Affinity DataIC50:  8nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639893(3-Ethoxy-5-{6-[2-(5-methoxy-benzo[b]thiophen-6-yl)...)
Affinity DataIC50:  8nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639894(5-{6-[2-(2,3-Dihydro-benzo[b]thiophen-5-yl)-ethyla...)
Affinity DataIC50:  8nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639895(3-Ethoxy-5-{6-[2-(6-fluoro-1-methyl-1H-indol-5-yl)...)
Affinity DataIC50:  8nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640225(3-(3-ethoxy-5-(6-((2-(7-fluoroquinolin-6-yl)ethyl)...)
Affinity DataIC50:  8nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataIC50:  8.90nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640246(4-{6-[2-(4-Fluoro-benzo[b]thiophen-5-yl)-ethylamin...)
Affinity DataIC50:  9nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639896(3-Ethoxy-5-{6-[2-(1-ethynyl-naphthalen-2-yl)-ethyl...)
Affinity DataIC50:  9nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM639897(4-{6-[2-(6-Methoxy-benzo[b]thiophen-5-yl)-ethylami...)
Affinity DataIC50:  10nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640309(2-Isopropoxy-4-{6-[2-(7-methoxy-5-methyl-2,3-dihyd...)
Affinity DataIC50:  10nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640227(4-Ethoxy-2-{6-[2-(1-methyl-naphthalen-2-yl)-ethyla...)
Affinity DataIC50:  10nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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