Compile Data Set for Download or QSAR
maximum 50k data
Found 335 with Last Name = 'macewan' and Initial = 'g'
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314350(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-meth...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314367(4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314357(4,6-dihydroxy-2-((1-methyl-4-phenyl-1H-pyrrolo[2,3...)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314361((Z)-4-hydroxy-2-((1-methyl-4-(4-(morpholine-4-carb...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314359(4-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)met...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314363((Z)-2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octane-3-ca...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314360(1-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)met...)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314346(1-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)met...)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314353((2Z)-4,6-dihydroxy-2-{[1-methyl-4-(4-methylpiperaz...)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314365(4-hydroxy-2-((1-methyl-4-(4-(4-methylpiperazine-1-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314362(4-hydroxy-2-((1-methyl-4-(4-(morpholine-4-carbonyl...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314368(4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314364(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octane-3-carbon...)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314351(2-((4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-1-meth...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314349(4-hydroxy-2-((1-methyl-4-morpholino-1H-pyrrolo[2,3...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314352(4-hydroxy-2-((1-methyl-4-(4-methylpiperazin-1-yl)-...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131518(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314366(4-hydroxy-2-((1-methyl-4-(4-(4-methylpiperazine-1-...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314332(4-hydroxy-2-((1-methyl-4-phenyl-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314332(4-hydroxy-2-((1-methyl-4-phenyl-1H-pyrrolo[2,3-b]p...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of Matrix metalloprotein-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162738(1-Benzoyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131523((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydro...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162730(4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314369(2-((1-ethyl-4-(4-(4-(2-hydroxyethyl)piperazine-1-c...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162742(4-(4-But-2-ynyloxy-benzenesulfonyl)-5-hydroxycarba...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131519(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162744(1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydrox...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131516(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyac...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131527((R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314317((Z)-1-(2-((4-(4-(3-oxa-8-azabicyclo[3.2.1]octane-8...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314327((Z)-1-(2-((4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314344(4-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)met...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131519(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314344(4-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)met...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM26550(2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamid...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162735(CHEMBL369574 | {2-[4-(4-But-2-ynyloxy-benzenesulfo...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162731(1-Benzyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150253(4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(furan-2-car...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131530(2-(4-(but-2-ynyloxy)-N-(pyridin-3-ylmethyl)phenyls...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314322((Z)-1-(2-((4-(2-oxa-5-azabicyclo[2.2.2]octan-5-yl)...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131520(2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of Matrix metalloprotein 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162740(4-(4-But-2-ynyloxy-benzenesulfonyl)-1,1-dioxo-1lam...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314342((Z)-1-(2-((1-methyl-4-(4-(pyrrolidine-1-carbonyl)p...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314339((Z)-1-(2-((4-(4-(3-methoxypyrrolidine-1-carbonyl)p...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314335((Z)-N-methyl-1-(1-methyl-3-((3-oxo-5-(3-pyridin-3-...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131531(2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of Matrix metalloprotein 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50131529(3-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Matrix metalloprotein 1 at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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