Compile Data Set for Download or QSAR
maximum 50k data
Found 40 with Last Name = 'macmaster' and Initial = 'jf'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50102249((S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113219(CHEMBL68075 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phe...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25924(N,12-dimethyl-14,15,17-triazatetracyclo[8.7.0.0^{3...)
Affinity DataIC50:  11nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113230(BMS-337197 | CHEMBL64830 | N-{2-[2-(3-Methoxy-4-ox...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113233(CHEMBL66614 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phe...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113215(CHEMBL67036 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phe...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113227(2-Dimethylamino-N-{2-[2-(3-methoxy-4-oxazol-5-yl-p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113216(CHEMBL302967 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-ph...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25920(N,12-dimethyl-11,14,17-triazatetracyclo[8.7.0.0^{3...)
Affinity DataIC50:  18nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25922(2-({12-methyl-11,14,17-triazatetracyclo[8.7.0.0^{3...)
Affinity DataIC50:  18nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113213(CHEMBL306453 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-ph...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113224((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-oxazol-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113229(2-tert-Butylamino-N-{2-[2-(3-methoxy-4-oxazol-5-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113225(CHEMBL305977 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-ph...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25921(benzimidazoquinoxaline analogue, 7b | methyl[2-({1...)
Affinity DataIC50:  23nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113221((3-Methoxy-4-oxazol-5-yl-phenyl)-[5-(2-methoxy-phe...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113223((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-o-tolyl-oxazol...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113212((3-Methoxy-4-oxazol-5-yl-phenyl)-(4-methyl-5-pheny...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113214(CHEMBL65826 | N-{2-[2-(3-Methoxy-4-oxazol-5-yl-phe...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25927(benzopyrazoloquinazoline analogue, 13b | methyl[2-...)
Affinity DataIC50:  35nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25923(12-methyl-N-[2-(piperidin-1-yl)ethyl]-11,14,17-tri...)
Affinity DataIC50:  46nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25926(N-(2-aminoethyl)-12-methyl-12,14,17-triazatetracyc...)
Affinity DataIC50:  58nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113222((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-m-tolyl-oxazol...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113220((3-Methoxy-4-oxazol-5-yl-phenyl)-(5-p-tolyl-oxazol...)
Affinity DataIC50:  85nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113232((4-Ethyl-5-phenyl-oxazol-2-yl)-(3-methoxy-4-oxazol...)
Affinity DataIC50:  86nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113231((3-Methoxy-4-oxazol-5-yl-phenyl)-[5-(3-methoxy-phe...)
Affinity DataIC50:  97nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113218(2-[2-(3-Methoxy-4-oxazol-5-yl-phenylamino)-oxazol-...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113211((3-Methoxy-4-oxazol-5-yl-phenyl)-[5-(4-methoxy-phe...)
Affinity DataIC50:  115nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113217(2-[2-(3-Methoxy-4-oxazol-5-yl-phenylamino)-oxazol-...)
Affinity DataIC50:  127nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50113228(2-[2-(3-Methoxy-4-oxazol-5-yl-phenylamino)-oxazol-...)
Affinity DataIC50:  141nMAssay Description:Inhibition of human inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25920(N,12-dimethyl-11,14,17-triazatetracyclo[8.7.0.0^{3...)
Affinity DataIC50:  230nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25919(BMS-345541 | BMS345541 | CHEMBL471496 | N-(2-amino...)
Affinity DataIC50:  300nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25921(benzimidazoquinoxaline analogue, 7b | methyl[2-({1...)
Affinity DataIC50:  390nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25924(N,12-dimethyl-14,15,17-triazatetracyclo[8.7.0.0^{3...)
Affinity DataIC50:  670nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25922(2-({12-methyl-11,14,17-triazatetracyclo[8.7.0.0^{3...)
Affinity DataIC50:  870nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25925(N,12-dimethyl-12,14,17-triazatetracyclo[8.7.0.0^{3...)
Affinity DataIC50:  990nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25926(N-(2-aminoethyl)-12-methyl-12,14,17-triazatetracyc...)
Affinity DataIC50:  1.60E+3nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25923(12-methyl-N-[2-(piperidin-1-yl)ethyl]-11,14,17-tri...)
Affinity DataIC50:  1.70E+3nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM25919(BMS-345541 | BMS345541 | CHEMBL471496 | N-(2-amino...)
Affinity DataIC50:  4.00E+3nMpH: 8.0 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed