Affinity DataKi: 0.00365nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00455nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00465nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00482nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00484nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00508nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00520nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00522nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0131nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.000190nMAssay Description:Tested for inhibition against P. carinii DHFR (dihydrofolate reductase)More data for this Ligand-Target Pair
Affinity DataIC50: 0.000530nMAssay Description:Inhibition against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.000530nMAssay Description:Tested for inhibition against Dihydrofolate reductase from P. cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 0.000530nMAssay Description:Tested for inhibition against Dihydrofolate reductase from P. cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00160nMAssay Description:Tested for inhibition against Dihydrofolate reductase from T. gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00160nMAssay Description:Inhibition against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.00210nMAssay Description:Inhibition against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00250nMAssay Description:Tested for inhibition against rat liver DHFR (dihydrofolate reductase)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: 2.41E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Southern Research
Curated by ChEMBL
Southern Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant full length C-terminal MYC/DDk-tagged DHODH using decylubiquinone as substrate measured for 1 hr by DCIP absorbance a...More data for this Ligand-Target Pair