Compile Data Set for Download or QSAR
maximum 50k data
Found 44 with Last Name = 'magrone' and Initial = 'p'
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Affinity DataKi:  0.0350nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50135594((+/-)-2-(6-chloropyridin-3-yl)-9-aza-bicyclo[4.2.1...)
Affinity DataKi:  0.270nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity to alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in rat cerebral membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  1.33nMAssay Description:Displacement of [3H]cystisine from alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261762((+/-)-exo-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50261766((+/-)-exo-(1R,2R,4R)-2-(6-chloropyridin-3-yl)-7-az...)
Affinity DataKi:  7.60nMAssay Description:Binding affinity to alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50035398((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50035398((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261764((+/-)-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261763((+/-)-endo-(1R,2R,4R)-2-(3-methylisoxazol-5-yl)-7-...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261763((+/-)-endo-(1R,2R,4R)-2-(3-methylisoxazol-5-yl)-7-...)
Affinity DataKi:  230nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50155639(Acetaldehyde O-((S)-1-methyl-pyrrolidin-2-ylmethyl...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261765((-/+)-7-methyl-2-(3-methylisoxazol-5-yl)-7-aza-bic...)
Affinity DataKi:  394nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332839(CHEMBL1630288 | anti(2S,5'S)-(+)-5b3-Methyl-5-pyrr...)
Affinity DataKi:  440nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  469nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261765((-/+)-7-methyl-2-(3-methylisoxazol-5-yl)-7-aza-bic...)
Affinity DataKi:  514nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)
Affinity DataKi:  520nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50035398((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50035398((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50261764((+/-)-2-(3-methylisoxazol-5-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50135594((+/-)-2-(6-chloropyridin-3-yl)-9-aza-bicyclo[4.2.1...)
Affinity DataKi:  2.79E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50135594((+/-)-2-(6-chloropyridin-3-yl)-9-aza-bicyclo[4.2.1...)
Affinity DataKi:  2.79E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Wistar rat hindlimb muscleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332836(CHEMBL1630294 | syn(2S,5'R)-(-)-3-Methoxy-5-(1-met...)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332842(CHEMBL1630291 | syn(2S,5'R)-(-)-3-Bromo-5-(1-methy...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332841(CHEMBL1630290 | syn(2S,5'R)-(-)-3-Bromo-5-pyrrolid...)
Affinity DataKi:  4.20E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332839(CHEMBL1630288 | anti(2S,5'S)-(+)-5b3-Methyl-5-pyrr...)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332836(CHEMBL1630294 | syn(2S,5'R)-(-)-3-Methoxy-5-(1-met...)
Affinity DataKi:  1.03E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332835(CHEMBL1630293 | anti(2S,5'S)-(+)-3-Methoxy-5-pyrro...)
Affinity DataKi:  1.13E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332840(CHEMBL1630289 | syn(2S,5'R)-(-)-3-Methyl-5-(1-meth...)
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332838(CHEMBL1630287 | syn(2S,5'R)-(-)-3-Methyl-5-pyrroli...)
Affinity DataKi:  1.80E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332834(CHEMBL1630292 | syn(2S,5'R)-(-)-3-Methoxy-5-pyrrol...)
Affinity DataKi:  2.80E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332841(CHEMBL1630290 | syn(2S,5'R)-(-)-3-Bromo-5-pyrrolid...)
Affinity DataKi:  3.50E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332838(CHEMBL1630287 | syn(2S,5'R)-(-)-3-Methyl-5-pyrroli...)
Affinity DataKi:  4.00E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332842(CHEMBL1630291 | syn(2S,5'R)-(-)-3-Bromo-5-(1-methy...)
Affinity DataKi:  4.30E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)
Affinity DataKi:  4.90E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50155639(Acetaldehyde O-((S)-1-methyl-pyrrolidin-2-ylmethyl...)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332835(CHEMBL1630293 | anti(2S,5'S)-(+)-3-Methoxy-5-pyrro...)
Affinity DataKi:  5.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50332837(CHEMBL1630295 | anti(2S,5'S)-(+)-3-tert-butoxy-5-p...)
Affinity DataKi:  1.84E+5nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332834(CHEMBL1630292 | syn(2S,5'R)-(-)-3-Methoxy-5-pyrrol...)
Affinity DataKi:  2.77E+5nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332840(CHEMBL1630289 | syn(2S,5'R)-(-)-3-Methyl-5-(1-meth...)
Affinity DataKi:  3.25E+5nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50332837(CHEMBL1630295 | anti(2S,5'S)-(+)-3-tert-butoxy-5-p...)
Affinity DataKi: >5.00E+5nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed