Found 187 with Last Name = 'malladi' and Initial = 'ss' 
Affinity DataIC50: 48nMAssay Description:Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced IL-8 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-TNF-alpha release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced IL-8 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced TNF-alpha release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced IL-6 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced IL-6 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced CXCL10 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced CCL2 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR7 in human PBMC assessed as inhibition of gardiquimod-induced IL-1beta release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced IL-1beta release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced CXCL10 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TLR8 in human PBMC assessed as inhibition of CL075-induced CCL2 release after 12 hrs by bead array assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Antagonist activity at TLR7 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of 250 ug/ml of gardiquimod-induc...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.79E+3nMAssay Description:Antagonist activity at TLR7 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of 1 ug/ml of gardiquimod-induced...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human TLR7 expressed in HEK-Blue cells assessed as inhibition of gardiquimod-induced NFkappaB activation by sAP reporter gene ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at human TLR8 expressed in HEK-Blue cells assessed as inhibition of CL075-induced NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.02E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.55E+3nMAssay Description:Antagonist activity at TLR8 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of CL075-induced NF-kappaB activa...More data for this Ligand-Target Pair
Affinity DataIC50: 4.65E+3nMAssay Description:Antagonist activity at human TLR8 expressed in HEK-Blue cells assessed as inhibition of CL075-induced NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.78E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.81E+3nMAssay Description:Antagonist activity at TLR8 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of CL075-induced NF-kappaB activa...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.24E+3nMAssay Description:Agonist activity at human TLR7 expressed in HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Antagonist activity at TLR7 (unknown origin) expressed in HEK293 cells by spectrophotometry in presence of 250 ng/mL gardiquimodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.58E+3nMAssay Description:Antagonist activity at TLR7 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of 1 ug/ml of gardiquimod-induced...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD2 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 1(Homo sapiens (Human))
University Of Kansas
Curated by ChEMBL
University Of Kansas
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human NOD1 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liq...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Antagonist activity at TLR8 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of CL075-induced NF-kappaB activa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Antagonist activity at TLR7 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of 1 ug/ml of gardiquimod-induced...More data for this Ligand-Target Pair
