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Found 172 with Last Name = 'manao' and Initial = 'g'
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50256796(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Affinity DataKi:  270nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50256796(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Affinity DataKi:  340nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50379825(CHEMBL2011701)
Affinity DataKi:  1.20E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257418(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Affinity DataKi:  2.23E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257294(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphenyl-4...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257418(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Affinity DataKi:  2.68E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257294(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphenyl-4...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257294(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphenyl-4...)
Affinity DataKi:  2.91E+4nMAssay Description:Inhibition of human cloned PTP1B expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50214527(4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human protein-tyrosine phosphatase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257478(2-(4'-Hydroxyphenyl)-3-[(4''carboxy-3''-hydroxy-1,...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50086976(4''-(2-Butyl-benzofuran-3-yl)-biphenyl-4-ol | 4'-(...)
Affinity DataIC50:  740nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human low molecular weight Protein-tyrosine phosphatase IF1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257478(2-(4'-Hydroxyphenyl)-3-[(4''carboxy-3''-hydroxy-1,...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human cloned PTP1B expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257477(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(4''carboxy-3''-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human cloned PTP1B expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50256813((3-(4'-hydroxybiphenyl-4-yl)benzofuran-2-yl)(4-hyd...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267098(4-{[5-(4-Benzyloxybenzylidene)-4-oxo-2-phenylimino...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of GST-tagged human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50256796(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human protein-tyrosine phosphatase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50214536(4-[5-(3-benzyloxybenzylidene)-2,4-dioxothiazolidin...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267069(4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of GST-tagged human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50086945(4''-(2-Butyl-benzofuran-3-ylmethyl)-biphenyl-4-ol ...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257477(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(4''carboxy-3''-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50214527(4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human T cell protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50379825(CHEMBL2011701)
Affinity DataIC50:  1.40E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50214527(4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267100(4-[(5-Naphthalen-2-ylmethylene-4-oxo-2-phenylimino...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of GST-tagged human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267068(4-{[4-Oxo-5-(3-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of GST-tagged human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50256796(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human cloned PTP1B expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50086928(2-(4'-(2-butylbenzofuran-3-yl)biphenyl-4-yloxy)ace...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257477(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(4''carboxy-3''-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50379831(CHEMBL2011699)
Affinity DataIC50:  2.20E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50379825(CHEMBL2011701)
Affinity DataIC50:  2.20E+3nMAssay Description:Competitive inhibition of human recombinant TCPTP using p-nitrophenylphosphate as substrate by Line-Weaver Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50379829(CHEMBL2011702)
Affinity DataIC50:  2.40E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50214527(4-((5-(4-(benzyloxy)benzylidene)-2,4-dioxothiazoli...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human low molecular weight Protein-tyrosine phosphatase IF1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50379827(CHEMBL2011704)
Affinity DataIC50:  2.50E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50214529(4-[5-(4-hydroxy-3-methoxybenzylidene)-2,4-dioxothi...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50267098(4-{[5-(4-Benzyloxybenzylidene)-4-oxo-2-phenylimino...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human T cell protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50214530(4-[2,4-dioxo-5-(4-phenoxybenzylidene)thiazolidin-3...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50379834(CHEMBL2011706)
Affinity DataIC50:  3.00E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50256796(6,7-Dihydroxy-2-(4'-hydroxyphenyl)-3-[(1,1'-biphen...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50267070(4-{[5-(3-Benzyloxybenzylidene)-4-oxo-2-phenylimino...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50267069(4-{[4-Oxo-5-(4-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50267100(4-[(5-Naphthalen-2-ylmethylene-4-oxo-2-phenylimino...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50267070(4-{[5-(3-Benzyloxybenzylidene)-4-oxo-2-phenylimino...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of GST-tagged human PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50379825(CHEMBL2011701)
Affinity DataIC50:  4.00E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Lin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50257476(2-(4'-Hydroxyphenyl)-3-[(3'',4''-dihydroxy-1,1'-bi...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human cloned PTP1B expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50379826(CHEMBL2011705)
Affinity DataIC50:  5.10E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50240530(3-(biphenyl-4-ylmethyl)-7-hydroxy-2-(4-hydroxybenz...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50267068(4-{[4-Oxo-5-(3-phenoxybenzylidene)-2-phenyliminoth...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of GST-tagged human LMW PTP1B IF1 isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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