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Found 31 with Last Name = 'manly' and Initial = 'sp'
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50067734((-)-(6aR-trans)-6,6,9-trimethyl-3-pentyl-6a,7,10,1...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092347(CHEMBL3586106)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092347(CHEMBL3586106)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092343(CHEMBL3586110)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM84880(THC, 8 beta-OH)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50067734((-)-(6aR-trans)-6,6,9-trimethyl-3-pentyl-6a,7,10,1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM84880(THC, 8 beta-OH)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092345(CHEMBL3586108)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092345(CHEMBL3586108)
Affinity DataKi:  129nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092344(CHEMBL3586109)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092344(CHEMBL3586109)
Affinity DataKi:  335nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092346(CHEMBL3586107)
Affinity DataKi:  830nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092343(CHEMBL3586110)
Affinity DataKi:  912nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092348(CHEMBL3586104)
Affinity DataKi:  1.91E+3nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092342(CHEMBL3586111)
Affinity DataKi:  2.14E+3nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092348(CHEMBL3586104)
Affinity DataKi:  3.22E+3nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092346(CHEMBL3586107)
Affinity DataKi:  3.27E+3nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092342(CHEMBL3586111)
Affinity DataKi:  5.67E+3nMAssay Description:Displacement of [3H]CP55940 from full length human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50491190(CHEMBL2375656)
Affinity DataKi:  7.31E+3nMAssay Description:Displacement of [3H]-enkephalin from human delta opioid receptor transfected in CHOK1 cells after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50350090(CHEMBL1813662)
Affinity DataIC50:  5.40E+3nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO-K1 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50350092(CHEMBL1811938)
Affinity DataIC50:  7.20E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO-K1 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50069242((6aR,10aS)-4-Methoxy-7,9-dimethyl-4,6,6a,7,8,10a-h...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of p56 lck autophosphorylation, gamma-[33P]-ATP incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50491190(CHEMBL2375656)
Affinity DataIC50:  1.46E+4nMAssay Description:Displacement of [3H]-enkephalin from human delta opioid receptor transfected in CHOK1 cells after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50350089(CHEMBL1813666)
Affinity DataIC50:  1.52E+4nMAssay Description:Displacement of [3H]CP-55,940 from human CB1 receptor expressed in CHO-K1 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50350089(CHEMBL1813666)
Affinity DataIC50:  1.99E+4nMAssay Description:Displacement of [3H]CP-55,940 from human CB2 receptor expressed in CHO-K1 cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50350091(CHEMBL1813663)
Affinity DataIC50:  3.24E+4nMAssay Description:Displacement of [3H]nor-Binaltorphimine from human kappa opioid receptor expressed in CHO-K1 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50069242((6aR,10aS)-4-Methoxy-7,9-dimethyl-4,6,6a,7,8,10a-h...)
Affinity DataIC50:  2.85E+5nMAssay Description:Inhibition of p72 syk autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human delta opioid receptor transfected in CHOK1 cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50491190(CHEMBL2375656)
Affinity DataEC50:  239nMAssay Description:Agonist activity at human delta opioid receptor transfected in CHOK1 cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed