TargetCalcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: <10nMAssay Description:Inhibition of wild-type human full length CAMK1A (M1 to L370 residues) expressed in bacterial expression system assessed as residual activity at 50 n...More data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: <10nMAssay Description:Inhibition of wild-type human partial length HIPK1 (M146 to I555 residues) expressed in mammalian expression system assessed as residual activity at ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: <10nMAssay Description:Inhibition of wild-type human partial length PIM1 (A15 to K313 residues) expressed in bacterial expression system assessed as residual activity at 50...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: <10nMAssay Description:Inhibition of wild-type human partial length DYRK1A (H129 to S509 residues) expressed in mammalian expression system assessed as residual activity at...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant CDK5 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated peptide as substrate after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant CDK2 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated peptide as substrate after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant CDK1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated peptide as substrate after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant CDK9 (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotinylated peptide as substrate after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK4/CyclinD1 (unknown origin) assessed as reduction in retinoblastoma phosphorylation at S473 residue by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4/CyclinD1 (unknown origin) assessed as reduction in retinoblastoma phosphorylation at S473 residue by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Abl1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of EGFR (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of Src (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of EGFR (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of Src (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of Abl1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of Abl1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of FGFR1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analys...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of FGFR1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analys...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Inhibition of Abl1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Inhibition of FGFR1 (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analys...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of EGFR (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataIC50: 243nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >500nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 642nMAssay Description:Inhibition of Src (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 645nMAssay Description:Inhibition of Src (unknown origin) assessed as incorporation of [32P] gamma-ATP in to myelin basic protein after 30 mins by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair