Found 61 with Last Name = 'matuszczak' and Initial = 'b' TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 279nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human 17beta-HSD2 expressed in HEK293 cells using estradiol as substrate after 10 mins in presence of radiolabeled tracer s...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human 17beta-HSD2 expressed in HEK293 cells using estradiol as substrate after 10 mins in presence of radiolabeled tracer s...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant human 17beta-HSD2 expressed in HEK293 cells using estradiol as substrate after 10 mins in presence of radiolabeled tracer s...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant human 17beta-HSD2 expressed in HEK293 cells using estradiol as substrate after 10 mins in presence of radiolabeled tracer s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of bovine lens ALR2 assessed as reduction of D,L-glyceraldehyde by spectrophotometryMore data for this Ligand-Target Pair
3D Structure (crystal)TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human sEH preincubated for 10 mins followed by PHOME substrate addition and measured after 60 mins by fluorescence-based as...More data for this Ligand-Target Pair
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of bovine lens ALR2 assessed as reduction of D,L-glyceraldehyde by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Innsbruck
Curated by ChEMBL
University Of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of 5-LO in human neutrophils preincubated for 10 mins followed by Ca2+ ionophore A23187 addition and measured after 10 mins by RP-HPLC ana...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human 17beta-HSD2 expressed in HEK293 cells using estradiol as substrate after 10 mins in presence of radiolabeled tracer s...More data for this Ligand-Target Pair
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of bovine lens ALR2 assessed as reduction of D,L-glyceraldehyde by spectrophotometryMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University of Innsbruck
Curated by ChEMBL
University of Innsbruck
Curated by ChEMBL
Affinity DataIC50: 4.09E+3nMAssay Description:Inhibition of recombinant human 17beta-HSD2 expressed in HEK293 cells using estradiol as substrate after 10 mins in presence of radiolabeled tracer s...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of bovine lens ALR2 assessed as reduction of D,L-glyceraldehyde by spectrophotometryMore data for this Ligand-Target Pair
