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Found 193 with Last Name = 'mcallister' and Initial = 'hm'
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209809(4-(3-(dimethylamino)-1-(4-(3-(piperidin-1-yl)propo...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209802(CHEMBL438490 | N,N-dimethyl-3-phenoxy-3-(4-(3-(pip...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209815(3-(3-methoxyphenoxy)-N,N-dimethyl-3-(4-(3-(piperid...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209806(CHEMBL245307 | N,N-dimethyl-3-phenyl-3-(3-(3-(pipe...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209810(CHEMBL245516 | N,N-dimethyl-3-(4-(3-(piperidin-1-y...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209812((4-(3-(dimethylamino)-1-phenoxypropyl)phenyl)(4-is...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209816(3-(4-(1-isopropylpiperidin-4-yloxy)phenyl)-N,N-dim...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209799(3-(3,4-dichlorophenoxy)-N,N-dimethyl-3-(4-(3-(pipe...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209813(CHEMBL246125 | N,N-dimethyl-3-(4-nitrophenoxy)-3-(...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209805(3-(3-chlorophenoxy)-N,N-dimethyl-3-(4-(3-(piperidi...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209800(CHEMBL394321 | N,N-dimethyl-3-(4-(methylthio)pheno...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209799(3-(3,4-dichlorophenoxy)-N,N-dimethyl-3-(4-(3-(pipe...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209799(3-(3,4-dichlorophenoxy)-N,N-dimethyl-3-(4-(3-(pipe...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209807(3-(4-fluorophenoxy)-N,N-dimethyl-3-(4-(3-(piperidi...)
Affinity DataKi:  1nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209820(3-(4-methoxyphenoxy)-N,N-dimethyl-3-(4-(3-(piperid...)
Affinity DataKi:  1nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209803(3-(3-bromophenoxy)-N,N-dimethyl-3-(4-(3-(piperidin...)
Affinity DataKi:  1nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209811(CHEMBL248377 | N,N-dimethyl-3-phenyl-3-(4-(3-(pipe...)
Affinity DataKi:  1nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209802(CHEMBL438490 | N,N-dimethyl-3-phenoxy-3-(4-(3-(pip...)
Affinity DataKi:  1nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209804(CHEMBL245515 | N,N-dimethyl-3-phenoxy-3-(4-(4-(pip...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209800(CHEMBL394321 | N,N-dimethyl-3-(4-(methylthio)pheno...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209807(3-(4-fluorophenoxy)-N,N-dimethyl-3-(4-(3-(piperidi...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209810(CHEMBL245516 | N,N-dimethyl-3-(4-(3-(piperidin-1-y...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209819(3-(4-chlorophenoxy)-N,N-dimethyl-3-(4-(3-(piperidi...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209817(3-(4-bromophenoxy)-N,N-dimethyl-3-(4-(3-(piperidin...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50199593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  2nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198590(4-(4-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198590(4-(4-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  2nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50199593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50199601(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(3-methoxy...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50199600(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50199593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-2-methyl-4-(...)
Affinity DataKi:  2nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  2nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209820(3-(4-methoxyphenoxy)-N,N-dimethyl-3-(4-(3-(piperid...)
Affinity DataKi:  2nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209815(3-(3-methoxyphenoxy)-N,N-dimethyl-3-(4-(3-(piperid...)
Affinity DataKi:  2nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50199597(2-methyl-4-(4-(methylthio)phenyl)-7-(3-morpholinop...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50199597(2-methyl-4-(4-(methylthio)phenyl)-7-(3-morpholinop...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209814((4-(3-(dimethylamino)-1-(4-(trifluoromethyl)phenox...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209819(3-(4-chlorophenoxy)-N,N-dimethyl-3-(4-(3-(piperidi...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209803(3-(3-bromophenoxy)-N,N-dimethyl-3-(4-(3-(piperidin...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50199603(4-(4-ethoxyphenyl)-7-(3-(4-fluoropiperidin-1-yl)pr...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity at rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50209808(CHEMBL248375 | N,N-dimethyl-3-(4-(3-(piperidin-1-y...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity at human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50198593(7-(3-(4-fluoropiperidin-1-yl)propoxy)-4-(4-methoxy...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity at human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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