TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:In vitro binding affinity for serotonin transporter RB5-HT-T in rat cortical membranes by [3H]-Citalopram displacement.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Antagonism of 5-hydroxytryptamine 1A receptor was determined in vitro using a [35S]-GTP-gammaS,More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.10nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 4.62nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:In vitro binding affinity towards Alpha-1 adrenergic receptor was determined by the displacement of [3H]prazosinMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.90nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5HTT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7.5nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair