TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assayMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assayMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Bethesda
Curated by ChEMBL
National Cancer Institute-Bethesda
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assayMore data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase cyp51A(Neosartorya fumigata (strain ATCC MYA-4609 / Af293...)
Swansea University
Curated by ChEMBL
Swansea University
Curated by ChEMBL
Affinity DataKd: 1.01E+3nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase cyp51A(Neosartorya fumigata (strain ATCC MYA-4609 / Af293...)
Swansea University
Curated by ChEMBL
Swansea University
Curated by ChEMBL
Affinity DataKd: 2.69E+3nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase cyp51A(Neosartorya fumigata (strain ATCC MYA-4609 / Af293...)
Swansea University
Curated by ChEMBL
Swansea University
Curated by ChEMBL
Affinity DataKd: 3.63E+3nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme A expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 4.03E+3nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme B expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 103nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme B expressed in Escherichia coli assessed as tight binding affin...More data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme B expressed in Escherichia coli assessed as tight binding affin...More data for this Ligand-Target Pair
Affinity DataKd: 73nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme B expressed in Escherichia coli assessed as tight binding affin...More data for this Ligand-Target Pair
Affinity DataKd: 429nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme B expressed in Escherichia coli assessed as tight binding affin...More data for this Ligand-Target Pair
Affinity DataKd: 3.00E+3nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as binding constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.60nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.70nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.10nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair
Affinity DataEC50: 850nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 170nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 61nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 480nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as binding constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as binding constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 3.50E+3nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as binding constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase cyp51A(Neosartorya fumigata (strain ATCC MYA-4609 / Af293...)
Swansea University
Curated by ChEMBL
Swansea University
Curated by ChEMBL
Affinity DataKd: 1.19E+4nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetSterol 14-alpha demethylase cyp51A(Neosartorya fumigata (strain ATCC MYA-4609 / Af293...)
Swansea University
Curated by ChEMBL
Swansea University
Curated by ChEMBL
Affinity DataKd: 4.79E+3nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme A expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 423nMAssay Description:Binding affinity to Aspergillus fumigatus AF293 sterol 14-alpha demethylase isoenzyme B expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 29nMAssay Description:Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assayMore data for this Ligand-Target Pair