TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Inhibition of human recombinant IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after 10 mins by...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Noncompetitive inhibition of human recombinant IDO1 expressed in Escherichia coli by Michaelis-Menton nonlinear regression plot analysis in presence ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of human recombinant IDO1 expressed in yeast IS20-2B using tryptophan as substrate by methylene blue/ascorbate assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Inhibition of human recombinant IDO1 using L-tryptophan as substrate after 15 mins by Dixon plot analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Competitive inhibition of 6His-tagged human recombinant IDO expressed in Escherichia coli BL21DE3pLysMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Inhibition of IDO by cell-free assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataKi: 1.60E+5nMAssay Description:Noncompetitive inhibition of human recombinant IDO1 expressed in Escherichia coli BL21 by Lineweaver-Burk double-reciprocal plot analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 7.10nMAssay Description:Inhibition of IFN-gamma-stimulated IDO1 activity in human HeLa cells using L-tryptophan as substrate after 48 hrs by microplate reader analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 71nMpH: 7.4Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 7.4 after 60 mins by HPLC an...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of N-terminal His-tagged human recombinant IDO1 expressed in Escherichia coli using D-tryptophan as substrate by methylene blue/ascorbate ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human IDO1 transfected in HEK293T cells assessed as kynurenine formation using L-Trp as substrate after 7 hrsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human IDO1 transfected in HEK293T cells assessed as kynurenine formation using L-Trp as substrate after 7 hrsMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: <200nMAssay Description:Inhibition of N-terminal hexa-Histidine tagged human IDO1 expressed in Escherichia coli using L-tryptophan as substrate after 30 mins by HPLC analysi...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: <200nMAssay Description:Inhibition of N-terminal His-tagged human recombinant IDO1 expressed in Escherichia coli using tryptophan as substrate by UV-visible absorption spect...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal His-tagged human recombinant IDO1 expressed in Escherichia coli using L-tryptophan as substrate preincubated for 10 mins fol...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Sib Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 330nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Ludwig Center For Cancer Research Of The University Of Lausanne
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of mouse IDO1 expressed in mouse P815B cells using L-tryptophan substrate incubated for 18 hrs by HPLC based cellular assayMore data for this Ligand-Target Pair