BindingDB PrimarySearch

Found 96 with Last Name = 'ming' and Initial = 'zh'

Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

IC50: 1.5nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516498(CHEMBL4449612)

IC50: 2.40nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565712(CHEMBL4780196)

IC50: 3.5nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516488(CHEMBL4454810)

IC50: 5.5nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)

IC50: 7nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565719(CHEMBL4799551)

IC50: 7.10nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM28031(BMS-777607 | N-{4-[(2-amino-3-chloropyridin-4-yl)o...)

IC50: 7.60nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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3D Structure (crystal)

Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565713(CHEMBL4792576)

IC50: 7.90nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565715(CHEMBL4790015)

IC50: 8.10nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565701(CHEMBL4784644)

IC50: 8.30nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)

IC50: 8.40nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565717(CHEMBL4784431)

IC50: 9nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565714(CHEMBL4787904)

IC50: 9.40nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565708(CHEMBL4786987)

IC50: 9.5nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565700(CHEMBL4794496)

IC50: 9.70nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516492(CHEMBL4474232)

IC50: 9.90nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565700(CHEMBL4794496)

IC50: 10nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516487(CHEMBL4553056)

IC50: 11nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565700(CHEMBL4794496)

IC50: 11nMAssay Description:Inhibition of Axl (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565712(CHEMBL4780196)

IC50: 12nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516495(CHEMBL4443305)

IC50: 13nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565706(CHEMBL4793436)

IC50: 14nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565709(CHEMBL4786463)

IC50: 15nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565716(CHEMBL4779200)

IC50: 16nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565717(CHEMBL4784431)

IC50: 17nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516495(CHEMBL4443305)

IC50: 17nMAssay Description:Inhibition of recombinant human His-tagged VEGFR2 cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubate...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516489(CHEMBL4438194)

IC50: 18nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565710(CHEMBL4795648)

IC50: 20nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565706(CHEMBL4793436)

IC50: 22nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565702(CHEMBL4789492)

IC50: 22nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516489(CHEMBL4438194)

IC50: 23nMAssay Description:Inhibition of recombinant human His-tagged VEGFR2 cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubate...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565711(CHEMBL4790899)

IC50: 23nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565703(CHEMBL4787082)

IC50: 25nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565717(CHEMBL4784431)

IC50: 28nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565720(CHEMBL4778632)

IC50: 29nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516499(CHEMBL4591255)

IC50: 31nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565709(CHEMBL4786463)

IC50: 33nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516497(CHEMBL4592597)

IC50: 33nMAssay Description:Inhibition of human recombinant His-tagged cMET cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubated ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565699(CHEMBL4798752)

IC50: 36nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565705(CHEMBL4792804)

IC50: 39nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565707(CHEMBL4790527)

IC50: 42nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)

IC50: 45nMAssay Description:Inhibition of MET in human MKN-45 cells assessed as reduction in HGF-mediated autophosphorylationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516497(CHEMBL4592597)

IC50: 45nMAssay Description:Inhibition of recombinant human His-tagged VEGFR2 cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubate...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565700(CHEMBL4794496)

IC50: 45nMAssay Description:Inhibition of c-KIT (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM28031(BMS-777607 | N-{4-[(2-amino-3-chloropyridin-4-yl)o...)

IC50: 47nMAssay Description:Inhibition of HGF-induced cMET autophosphorylation in human MKN45 cells preincubated for 1 hr followed by HGF addition and measured after 10 mins by ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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3D Structure (crystal)

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565708(CHEMBL4786987)

IC50: 48nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565713(CHEMBL4792576)

IC50: 53nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565700(CHEMBL4794496)

IC50: 59nMAssay Description:Inhibition of MET in human MKN-45 cells assessed as reduction in HGF-mediated autophosphorylationMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50516487(CHEMBL4553056)

IC50: 63nMAssay Description:Inhibition of recombinant human His-tagged VEGFR2 cytoplasmic domain expressed in baculovirus expression system using biotin as substrate preincubate...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL

BDBM50565704(CHEMBL4776554)

IC50: 65nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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