TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132G](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 2.90nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 3.80nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 4.60nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 46nMT: 2°CAssay Description:For WT IDH1 and IDH2, reactions were conducted at room temperature in 384-well Greiner black microtiter plates in a total volume of 10 μL of ass...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial(Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 496nMT: 2°CAssay Description:For WT IDH1 and IDH2, reactions were conducted at room temperature in 384-well Greiner black microtiter plates in a total volume of 10 μL of ass...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial [R172S](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 1.03E+3nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 1.36E+3nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 4.50E+3nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 1.09E+4nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132G](Homo sapiens (Human))
Albert Einstein College of Medicine
Albert Einstein College of Medicine
Affinity DataIC50: 2.33E+4nMT: 2°CAssay Description:RapidFire-MS/MS measurements of mutant IDH1 and IDH2 reactions were conducted at room temperature in 384-well Greiner polypropylene microtiter plates...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair