Affinity DataKi: 0.0900nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Inhibition of human ERG expressed in HEK cells assessed as blockade of potassium tail current by standard patch clamp analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity at histamine H1 receptorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair