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Found 100 with Last Name = 'moy' and Initial = 'fj'
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143640(4-({5-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-napht...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143634(4-{[5-(4-Bromo-phenoxymethyl)-naphthalen-2-ylamino...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143650(4-{[5-(3-Chloro-phenoxymethyl)-naphthalen-2-ylamin...)
Affinity DataIC50:  3.10nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143617(CHEMBL442168 | N-{5-[2-(8-Chloro-quinolin-2-yl)-vi...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143630(CHEMBL299043 | N-{5-[(E)-2-(6-Chloro-quinolin-2-yl...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378568(CHEMBL1163016)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143627(C,C,C-Trifluoro-N-{5-[2-(6-methoxy-quinolin-2-yl)-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143623(CHEMBL299278 | N-{5-[2-(6-Dimethylamino-quinolin-2...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096468(CHEMBL76974 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096467(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143637(CHEMBL56633 | N-{5-[2-(4-Chloro-phenyl)-vinyl]-nap...)
Affinity DataIC50:  4.30nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143633(4-chloro-N-[({5-[(1E)-7-chloroquinolin-2-yl)vinyl]...)
Affinity DataIC50:  4.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143616(4-[(5-Phenoxymethyl-naphthalen-2-ylamino)-methyl]-...)
Affinity DataIC50:  4.80nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378568(CHEMBL1163016)
Affinity DataIC50:  5nMAssay Description:Inhibition of src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378568(CHEMBL1163016)
Affinity DataIC50:  5nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378568(CHEMBL1163016)
Affinity DataIC50:  5nMAssay Description:Inhibition of Abl 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143621(CHEMBL55390 | N-[5-(3-Chloro-benzyloxy)-naphthalen...)
Affinity DataIC50:  5.10nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096467(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096468(CHEMBL76974 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143638(CHEMBL57565 | N-[5-(3-Bromo-benzyloxy)-naphthalen-...)
Affinity DataIC50:  6.10nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143628(C,C,C-Trifluoro-N-{5-[2-(6-methyl-quinolin-2-yl)-v...)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143641(C,C,C-Trifluoro-N-{5-[2-(3-trifluoromethyl-phenyl)...)
Affinity DataIC50:  6.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143618(C,C,C-Trifluoro-N-{5-[2-(3-methoxy-phenyl)-vinyl]-...)
Affinity DataIC50:  6.60nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143635(CHEMBL440672 | N-[({5-[(1E)-7-chloroquinolin-2-yl)...)
Affinity DataIC50:  6.70nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143632(CHEMBL56307 | N-{5-[(E)-2-(3-Trifluoromethyl-pheny...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143646(4-({5-[(E)-2-(3-Trifluoromethyl-phenyl)-vinyl]-nap...)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143629(CHEMBL57465 | N-[5-(3-Trifluoromethyl-benzyloxy)-n...)
Affinity DataIC50:  7.40nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143625(C,C,C-Trifluoro-N-(5-styryl-naphthalen-2-yl)-metha...)
Affinity DataIC50:  7.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(CHEMBL70176 | N-Hydroxy-2-[(4-methoxy-benzenesulfo...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143636(4-methyl-N-[({5-[(1E)-7-chloroquinolin-2-yl)vinyl]...)
Affinity DataIC50:  8.30nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143615(C,C,C-Trifluoro-N-[5-(2-quinolin-2-yl-vinyl)-napht...)
Affinity DataIC50:  9.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143643(CHEMBL56642 | N-{5-[2-(4-Chloro-quinolin-2-yl)-vin...)
Affinity DataIC50:  10.5nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096471(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143619(C,C,C-Trifluoro-N-[5-(2-naphthalen-2-yl-vinyl)-nap...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143626(CHEMBL57617 | N-{5-[2-(7-Chloro-quinolin-2-yl)-vin...)
Affinity DataIC50:  15.1nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143620(CHEMBL52599 | N-[5-(3-Trifluoromethyl-phenoxymethy...)
Affinity DataIC50:  15.2nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143631(CHEMBL57169 | N-[5-(3-Chloro-phenoxymethyl)-naphth...)
Affinity DataIC50:  15.3nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378568(CHEMBL1163016)
Affinity DataIC50:  16nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143645(CHEMBL293304 | N-{5-[(E)-2-(7-Chloro-quinolin-2-yl...)
Affinity DataIC50:  17.4nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50143647(CHEMBL56741 | N-[5-(4-Bromo-phenoxymethyl)-naphtha...)
Affinity DataIC50:  21.3nMAssay Description:Inhibitory concentration against HCMV protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096469(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096474(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378568(CHEMBL1163016)
Affinity DataIC50:  24nMAssay Description:Inhibition of GCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096472(2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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