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Found 57 with Last Name = 'munoz' and Initial = 'e'
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197959(CHEMBL3943485)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197965(Incensole)
Affinity DataIC50:  2.10E+3nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197958(CHEMBL3979367)
Affinity DataIC50:  2.20E+3nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197963(CHEMBL3983336)
Affinity DataIC50:  5.80E+3nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50382731(CHEMBL2023564)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing p4xM67-tk-Luc treated 30 mins before TNFalpha challenge measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197964(CHEMBL3922508)
Affinity DataIC50:  1.23E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197969(CHEMBL3975348)
Affinity DataIC50:  1.32E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50335905((+)-(S)-ar-turmerone | CHEMBL1668333)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of IFN gamma-induced STAT3 (unknown origin) activation in HeLa-STAT3-Luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197965(Incensole)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197970(CHEMBL3913521)
Affinity DataIC50:  2.11E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197971(CHEMBL3890789)
Affinity DataIC50:  2.17E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197961(CHEMBL3899770)
Affinity DataIC50:  2.41E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197961(CHEMBL3899770)
Affinity DataIC50:  3.87E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197970(CHEMBL3913521)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197963(CHEMBL3983336)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197964(CHEMBL3922508)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197966(CHEMBL3959869)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197971(CHEMBL3890789)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197960(CHEMBL3931428)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197959(CHEMBL3943485)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197958(CHEMBL3979367)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197969(CHEMBL3975348)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197967(CHEMBL3948101)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197962(CHEMBL3894504)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197968(CHEMBL3904515)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197962(CHEMBL3894504)
Affinity DataIC50:  5.75E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50382730((-)-ALPHA-BISABOLOL | ALPHA-BISABOLOL)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing p4xM67-tk-Luc treated 30 mins before TNFalpha challenge measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197967(CHEMBL3948101)
Affinity DataIC50:  9.44E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197968(CHEMBL3904515)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197960(CHEMBL3931428)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50197958(CHEMBL3979367)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of NFkappaB p65 activation (unknown origin) expressed in human HeLa cells assessed as inhibition of TNFalpha-induced NFkappaB p65 nuclear ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197966(CHEMBL3959869)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50382732(CHEMBL2023565)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing p4xM67-tk-Luc treated 30 mins before TNFalpha challenge measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197971(CHEMBL3890789)
Affinity DataEC50:  1.20E+3nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197968(CHEMBL3904515)
Affinity DataEC50:  2.54E+4nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197964(CHEMBL3922508)
Affinity DataEC50:  7.30E+3nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197963(CHEMBL3983336)
Affinity DataEC50:  2.40E+3nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197960(CHEMBL3931428)
Affinity DataEC50:  3.01E+4nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197959(CHEMBL3943485)
Affinity DataEC50:  170nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50240432(1-hydroxy-5-methyl-2-isopropylbenzene | 2-isopropy...)
Affinity DataEC50:  2.90E+4nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50197958(CHEMBL3979367)
Affinity DataEC50:  1.60E+4nMAssay Description:Agonist activity at mouse YFP-tagged TRPV3 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-2-AM dye based microscopic analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50197961(CHEMBL3899770)
Affinity DataEC50:  5.60E+3nMAssay Description:Activation of rat TRPV3 overexpressed in HEK293 cells assessed as increase in 2-aminoethoxydiphenyl borate-induced intracellular calcium concentratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50061117(6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol |...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50541571(CHEMBL127671 | HU-336 | HU-345)
Affinity DataEC50:  2.31E+4nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50541572(CHEMBL4635276)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50541573(CHEMBL4636188)
Affinity DataEC50:  1.47E+4nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50541574(CHEMBL4636830)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50318484(2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50318486(2-Methyl-2-(4-methyl-pent-3-enyl)-7-pentyl-2H-chro...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50318487(CHEMBL497318 | Cannabigerol)
Affinity DataEC50:  1.57E+4nMAssay Description:Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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