Affinity DataIC50: 4nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Gpc Biotech
Curated by ChEMBL
Gpc Biotech
Curated by ChEMBL
Affinity DataIC50: <5nMAssay Description:Inhibition of Candida albicans Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Gpc Biotech
Curated by ChEMBL
Gpc Biotech
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of Candida albicans Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 7nM EC50: 80nMAssay Description:CAII assays were performed at CEREP (paris). All other kinase assays were performed at Upstate (Dundee, UK).More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Gpc Biotech
Curated by ChEMBL
Gpc Biotech
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Candida albicans Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
Affinity DataIC50: 14nM EC50: 40nMAssay Description:CAII assays were performed at CEREP (paris). All other kinase assays were performed at Upstate (Dundee, UK).More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 20nM EC50: 70nMAssay Description:CAII assays were performed at CEREP (paris). All other kinase assays were performed at Upstate (Dundee, UK).More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:In vitro kinase activity of PEGylated pyrazolopyrimidone CDK inhibitor or a 5 PEG-amine was coupled to ReactiGel agarose beads (Pierce, No. 20259).More data for this Ligand-Target Pair
Affinity DataIC50: 28nM EC50: <3nMAssay Description:CAII assays were performed at CEREP (paris). All other kinase assays were performed at Upstate (Dundee, UK).More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of HCT116 cell proliferation with compounds using calcein AM Assay.More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:In vitro kinase activity of PEGylated pyrazolopyrimidone CDK inhibitor or a 5 PEG-amine was coupled to ReactiGel agarose beads (Pierce, No. 20259).More data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Gpc Biotech
Curated by ChEMBL
Gpc Biotech
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of Candida albicans FarnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin B1More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
Affinity DataIC50: 221nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 282nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 372nM EC50: 70nMAssay Description:CAII assays were performed at CEREP (paris). All other kinase assays were performed at Upstate (Dundee, UK).More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
Affinity DataIC50: 485nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 663nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 754nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 839nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 858nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:In vitro kinase activity of PEGylated pyrazolopyrimidone CDK inhibitor or a 5 PEG-amine was coupled to ReactiGel agarose beads (Pierce, No. 20259).More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Mitotix
Curated by ChEMBL
Mitotix
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Mitotix
Curated by ChEMBL
Mitotix
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Mitotix
Curated by ChEMBL
Mitotix
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Mitotix
Curated by ChEMBL
Mitotix
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against cyclin-dependent kinase 4-cyclin D1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Mitotix
Curated by ChEMBL
Mitotix
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair