Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in GalCer accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Mus musculus)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mouse UGT8 assessed as redcution in SFT accumulationMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Affinity DataIC50: 10.9nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 39.2nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 55.7nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 63.9nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 66.5nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 73.8nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 77.5nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in SFT accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 203nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 241nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 287nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
Target2-hydroxyacylsphingosine 1-beta-galactosyltransferase(Homo sapiens)
Sanofi R&D
Curated by ChEMBL
Sanofi R&D
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of UGT8 in human OE19 cells assessed as redcution in GalCer accumulation measured after 72 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair