Affinity DataKi: 0.0400nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 133nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 309nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 399nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 500nM ΔG°: -35.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 500nM ΔG°: -35.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 648nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 700nM ΔG°: -34.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 700nM ΔG°: -34.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nM ΔG°: -32.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 1.53E+3nMAssay Description:Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nM ΔG°: -31.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nM ΔG°: -30.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nM ΔG°: -29.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 5.30E+3nM ΔG°: -29.8kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nM ΔG°: -29.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 6.15E+3nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 6.50E+3nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 7.70E+3nM ΔG°: -28.9kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 8.29E+3nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 8.70E+3nM ΔG°: -28.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 8.80E+3nM ΔG°: -28.6kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 9.20E+3nM ΔG°: -28.5kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 1.02E+4nM ΔG°: -28.2kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 1.09E+4nM ΔG°: -28.0kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 2.19E+4nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataKi: 2.43E+4nM ΔG°: -26.1kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 4.29E+4nM ΔG°: -24.7kJ/molepH: 7.4 T: 2°CAssay Description:The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o...More data for this Ligand-Target Pair
Affinity DataKi: 4.62E+4nMAssay Description:Binding affinity for Opioid receptor delta 1 using [3H]-DPDPE in rat brain P2 synaptosomal preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Opioid receptor mu 1 agonism in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Opioid receptor mu 1 agonism in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Opioid receptor mu 1 agonism in guinea pig ileumMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 61.9nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 70.4nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 70.7nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Inhibition of CDK4/Cyclin D1 expressed in Sf9 cells assessed as inhibition of Rb phosphorylationMore data for this Ligand-Target Pair