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maximum 50k data
Found 145 with Last Name = 'nagel' and Initial = 'd'
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  40nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597266(CHEMBL5200272)
Affinity DataIC50:  47nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597278(CHEMBL5196889)
Affinity DataIC50:  150nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597279(CHEMBL4537408)
Affinity DataIC50:  170nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597276(CHEMBL5177294)
Affinity DataIC50:  190nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597267(CHEMBL5201666)
Affinity DataIC50:  230nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597268(CHEMBL5171625)
Affinity DataIC50:  230nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597278(CHEMBL5196889)
Affinity DataIC50:  420nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597266(CHEMBL5200272)
Affinity DataIC50:  540nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597270(CHEMBL5195074)
Affinity DataIC50:  580nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597267(CHEMBL5201666)
Affinity DataIC50:  600nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260181(US9504692, 4116)
Affinity DataIC50:  690nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM260159(BDBM50177661 | US9504692, Mepezine)
Affinity DataIC50:  850nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM260190(US9504692, 3998)
Affinity DataIC50:  970nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM260193(US9504692, 4057)
Affinity DataIC50:  973nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597276(CHEMBL5177294)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607075(CHEMBL5220335)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260178(US9504692, 3916)
Affinity DataIC50:  1.18E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597275(CHEMBL5197372)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597274(CHEMBL5183589)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597277(CHEMBL5208691)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607067(CHEMBL5218475)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260172(US9504692, 3951)
Affinity DataIC50:  1.42E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597275(CHEMBL5197372)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597269(CHEMBL5190565)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597272(CHEMBL5209188)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597268(CHEMBL5171625)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607064(CHEMBL1730394)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607085(CHEMBL5221076)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260194(US9504692, 4090)
Affinity DataIC50:  1.75E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597271(CHEMBL5204820)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260191(US9504692, 4124)
Affinity DataIC50:  1.85E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM260191(US9504692, 4124)
Affinity DataIC50:  1.85E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607079(CHEMBL5219802)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260190(US9504692, 3998)
Affinity DataIC50:  2.00E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597269(CHEMBL5190565)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activity incubated for 25 min by ethidium bromide/bromophenol blue staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597277(CHEMBL5208691)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607076(CHEMBL5219391)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607069(CHEMBL5220721)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of wild-type Slack (unknown origin) expressed in HEK293 cells measured by whole-cell electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607069(CHEMBL5220721)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607064(CHEMBL1730394)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260189(US9504692, 3997)
Affinity DataIC50:  2.40E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily T member 1(Homo sapiens)
University Of North Texas Health Science Center

Curated by ChEMBL
LigandPNGBDBM50607085(CHEMBL5221076)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by thallium flux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM260192(US9504692, 4058)
Affinity DataIC50:  2.41E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM260180(US9504692, 4020)
Affinity DataIC50:  2.50E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM260177(US9504692, 4037)
Affinity DataIC50:  2.67E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM260164(US9504692, 3950)
Affinity DataIC50:  2.67E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM260173(US9504692, 3949)
Affinity DataIC50:  2.77E+3nMT: 2°CAssay Description:To screen for small molecular weight compounds that can inhibit MALT1 protease activity, recombinant GSTMALT1 was purified from E. coli to establish ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597279(CHEMBL4537408)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50597270(CHEMBL5195074)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 decatenation activity using kDNA as substrate incubated for 10 to 20 min by ethidium bromide/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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