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Found 60 with Last Name = 'nanavati' and Initial = 'nt'
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]-estradiol from estrogen receptor (ER)More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022231(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylm...)
Affinity DataIC50:  4.70nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022234(4-[4-(4-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmeth...)
Affinity DataIC50:  5.5nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022235(4-(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-...)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  8.5nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022233(4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022232(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-et...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site (AEBS)More data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022235(4-(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022233(4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022234(4-[4-(4-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmeth...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022231(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylm...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 3)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 5)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 2)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 6)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022232(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-et...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50020285(3'-Methoxy-4'Hydroxyclomiphene | 4-{2-Chloro-1-[4-...)
Affinity DataIC50:  22nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site (AEBS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50020286(4-{1-Chloro-2-[4-(2-diethylamino-ethoxy)-phenyl]-2...)
Affinity DataIC50:  32nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site (AEBS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016460((S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-prop...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022235(4-(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-...)
Affinity DataIC50:  290nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022231(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylm...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022233(4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022234(4-[4-(4-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmeth...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022232(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-et...)
Affinity DataIC50:  640nMAssay Description:Inhibitory activity against dihydrofolate reductase of Streptococcus faeciumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50020285(3'-Methoxy-4'Hydroxyclomiphene | 4-{2-Chloro-1-[4-...)
Affinity DataIC50:  780nMAssay Description:Displacement of [3H]-estradiol from estrogen receptor (ER)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022237((S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022235(4-(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50020286(4-{1-Chloro-2-[4-(2-diethylamino-ethoxy)-phenyl]-2...)
Affinity DataIC50:  3.00E+3nMAssay Description:Displacement of [3H]-estradiol from estrogen receptor (ER)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022231(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylm...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022236((S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022233(4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022232(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-et...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022234(4-[4-(4-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmeth...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022237((S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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