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Found 825 with Last Name = 'negri' and Initial = 'm'
TargetTransporter(Rattus norvegicus (rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308250((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Affinity DataKi:  0.135nMAssay Description:Displacement of [N-methyl-3H]nisoxetine from rat hippocampus NET by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308250((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Affinity DataKi:  0.851nMAssay Description:Displacement of [3H]citalopram from mouse cortex SERT by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]-citalopram from SERT in mouse cortex after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  1.58nMAssay Description:Displacement of [3H]nisoxetine from NET in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]nisoxetine from NET in rat hippocampus after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]WIN-35428 from DAT in mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50334247((R,E)-1-(4-(2-fluorophenyl)-4-o-tolylbut-3-enyl)pi...)
Affinity DataKi:  14.8nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50039251((R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-enyl)pi...)
Affinity DataKi:  17.0nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417649(CHEMBL1642396)
Affinity DataKi:  18.2nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417641(CHEMBL1642400)
Affinity DataKi:  19.1nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417627(CHEMBL1642378)
Affinity DataKi:  20.4nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417639(CHEMBL1642397)
Affinity DataKi:  21.9nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417626(CHEMBL1642376)
Affinity DataKi:  28.8nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417628(CHEMBL1642379)
Affinity DataKi:  29.5nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417631(CHEMBL1642384)
Affinity DataKi:  33.9nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417638(CHEMBL1642395)
Affinity DataKi:  38.0nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417642(CHEMBL1642401)
Affinity DataKi:  38.9nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417625(CHEMBL1642375)
Affinity DataKi:  40.7nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417637(CHEMBL1642394)
Affinity DataKi:  41.7nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417666(CHEMBL1642388)
Affinity DataKi:  46.8nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417640(CHEMBL1642398)
Affinity DataKi:  52.5nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417650(CHEMBL1642399)
Affinity DataKi:  53.7nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417629(CHEMBL1642381)
Affinity DataKi:  56.2nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417630(CHEMBL1642382)
Affinity DataKi:  58.9nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

LigandPNGBDBM39849(Amide and sulfonamide derivatives, 33)
Affinity DataKi:  60nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417635(CHEMBL1642391)
Affinity DataKi:  61.7nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417659(CHEMBL1642374)
Affinity DataKi:  69.2nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417665(CHEMBL1642393)
Affinity DataKi:  70.8nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50020891((R)-1-(4,4-Diphenyl-but-3-enyl)-piperidine-3-carbo...)
Affinity DataKi:  72.4nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417663(CHEMBL1642386)
Affinity DataKi:  72.4nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417632(CHEMBL1642385)
Affinity DataKi:  77.6nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

LigandPNGBDBM39856(Amide and sulfonamide derivatives, 41)
Affinity DataKi:  80nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

LigandPNGBDBM50115616(3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PH...)
Affinity DataKi:  80nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417633(CHEMBL1642387)
Affinity DataKi:  89.1nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417660(CHEMBL1642377)
Affinity DataKi:  93.3nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417620(CHEMBL1642367)
Affinity DataKi:  93.3nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

LigandPNGBDBM39819(Amide and sulfonamide derivatives, 3)
Affinity DataKi:  100nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417621(CHEMBL1642368)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

LigandPNGBDBM39820(Amide and sulfonamide derivatives, 4)
Affinity DataKi:  120nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417651(CHEMBL1642402)
Affinity DataKi:  138nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417664(CHEMBL1642389)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417618(CHEMBL1642364)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Northwestern University

LigandPNGBDBM39856(Amide and sulfonamide derivatives, 41)
Affinity DataKi:  170nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

LigandPNGBDBM39850(Amide and sulfonamide derivatives, 34)
Affinity DataKi:  200nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417619(CHEMBL1642365)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Northwestern University

LigandPNGBDBM50115616(3-(4-BENZENESULFONYL-THIOPHENE-2-SULFONYLAMINO)-PH...)
Affinity DataKi:  250nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417662(CHEMBL1642383)
Affinity DataKi:  331nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

LigandPNGBDBM39857(Amide and sulfonamide derivatives, 42)
Affinity DataKi:  340nMpH: 7.0Assay Description:Inhibition assay against beta lactamase enzymes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417634(CHEMBL1642390)
Affinity DataKi:  355nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417622(CHEMBL1642370)
Affinity DataKi:  372nMAssay Description:Displacement of [3H]Tiagabine from human recombinant GAT1 expressed in HEK293 cells by equilibrium binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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