Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2.60nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2.70nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.10nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.10nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.20nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.20nMpH: 7.5Assay Description:Compounds are assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP in...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.20nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.30nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.5nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.60nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.60nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3.70nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4nMpH: 7.5Assay Description:Compounds are assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP in...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4nMAssay Description:Assays are performed in 96-well format in a final volume of 60 μL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additi...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.10nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.20nMpH: 7.5Assay Description:Compounds are assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP in...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.30nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.30nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.40nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.60nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4.60nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human cathepsin G after 1 hr by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0 T: 2°CAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of ITK by DELFIA assayMore data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5nMAssay Description:Assays are performed in 96-well format in a final volume of 60 μL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additi...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5nMAssay Description:Assays are performed in 96-well format in a final volume of 60 μL/well, containing 100 mM potassium phosphate, pH 7.4, 1% (v/v) DMSO, and additi...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5.10nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5.20nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5.20nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 5.20nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair