Affinity DataKi: 0.300nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 16.4nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha7 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activation of rat alpha4beta2 nAChR by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 350nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+5nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 4.60E+3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta4 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human alpha3beta4 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 410nMAssay Description:Activation of human alpha4beta2 nAChR assessed as potentiation of submaximal response to nicotine induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 240nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 280nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 650nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 5.10nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair