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Found 39 with Last Name = 'nickisch' and Initial = 'k'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261565(CHEMBL4098239)
Affinity DataIC50:  7nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261578(CHEMBL4085932)
Affinity DataIC50:  65nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261559(CHEMBL4067116)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataIC50:  110nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261577(CHEMBL4077445)
Affinity DataIC50:  120nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261563(CHEMBL4089618)
Affinity DataIC50:  129nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261562(CHEMBL4068479)
Affinity DataIC50:  198nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261581(CHEMBL4086863)
Affinity DataIC50:  202nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261575(CHEMBL4102621)
Affinity DataIC50:  210nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261580(CHEMBL4100191)
Affinity DataIC50:  232nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261583(CHEMBL4081744)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261570(CHEMBL4071193)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261579(CHEMBL4064401)
Affinity DataIC50:  250nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261585(CHEMBL4073866)
Affinity DataIC50:  290nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261582(CHEMBL4083620)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  309nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261560(CHEMBL4094577)
Affinity DataIC50:  325nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261564(CHEMBL4059816)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015195(CHEMBL545363 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010833(CHEMBL552615 | CHEMBL99585 | Ersentilide | N-(4-{2...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015190(CHEMBL536800 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015194(CHEMBL11629 | N-[4-(2-Hydroxy-3-{2-[4-(2-methyl-im...)
Affinity DataIC50:  2.80E+3nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM25762(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261573(CHEMBL4098852)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM25762(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Affinity DataIC50:  9.00E+3nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261576(CHEMBL4078353)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261584(CHEMBL4062557)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human CA2 catalytic activity pre-incubated for 15 mins followed by 4-NPA substrate addition and measured every 12 to 15 secs for 5 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015191(CHEMBL11944 | N-[4-(2-Hydroxy-3-{2-[4-(2-methyl-im...)
Affinity DataIC50:  1.80E+4nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015196(CHEMBL542544 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50:  2.10E+4nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015190(CHEMBL536800 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50:  2.30E+4nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015193(CHEMBL543251 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50:  3.80E+4nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010833(CHEMBL552615 | CHEMBL99585 | Ersentilide | N-(4-{2...)
Affinity DataIC50:  4.70E+4nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015194(CHEMBL11629 | N-[4-(2-Hydroxy-3-{2-[4-(2-methyl-im...)
Affinity DataIC50:  5.70E+4nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015196(CHEMBL542544 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015195(CHEMBL545363 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015191(CHEMBL11944 | N-[4-(2-Hydroxy-3-{2-[4-(2-methyl-im...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50015193(CHEMBL543251 | N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  2.30nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Evestra

Curated by ChEMBL
LigandPNGBDBM50261561(CHEMBL4075710)
Affinity DataEC50:  432nMAssay Description:Binding affinity to ER (unknown origin) expressed in UAS-bla GripTite 293 cells by Select screen competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed