Affinity DataIC50: 3.30nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 14.4nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 21.4nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 21.4nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant full length IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of human purified insulin receptor expressed in HepG2 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 147nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Osi Pharmaceuticals
Curated by ChEMBL
Osi Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 148nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair