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Found 1069 with Last Name = 'nirschl' and Initial = 'd'
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50230322(CHEMBL4071545)
Affinity DataKi:  0.160nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525762(CHEMBL4467360)
Affinity DataKi:  0.270nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440220(CHEMBL2426624)
Affinity DataKi:  0.480nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440220(CHEMBL2426624)
Affinity DataKi:  0.480nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440216(CHEMBL2426648)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525762(CHEMBL4467360)
Affinity DataKi:  0.950nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50348410(CHEMBL1801004)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440230(CHEMBL2426639)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440233(CHEMBL2426636)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525770(CHEMBL4452300)
Affinity DataKi:  1.80nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525779(CHEMBL4550408)
Affinity DataKi:  1.80nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440214(CHEMBL2426650)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525772(CHEMBL4475559)
Affinity DataKi:  2.10nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525773(CHEMBL4460266)
Affinity DataKi:  2.20nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440220(CHEMBL2426624)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440232(CHEMBL2426637)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440220(CHEMBL2426624)
Affinity DataKi:  2.40nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440246(CHEMBL2426658)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50063669(CHEMBL3398641)
Affinity DataKi:  2.70nMAssay Description:Inhibition of activated coagulation factor 11 (unknown origin) assessed as inhibitory constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440215(CHEMBL2426649)
Affinity DataKi:  4nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525771(CHEMBL4465144)
Affinity DataKi:  4.40nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525769(CHEMBL4551053)
Affinity DataKi:  4.70nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525761(CHEMBL4463167)
Affinity DataKi:  4.80nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440244(CHEMBL2426660)
Affinity DataKi:  5nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440243(CHEMBL2426662)
Affinity DataKi:  5.10nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525763(CHEMBL4438562)
Affinity DataKi:  5.30nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440209(CHEMBL2426656)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440219(CHEMBL2426665)
Affinity DataKi:  6nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440242(CHEMBL2426663)
Affinity DataKi:  6.70nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440212(CHEMBL2426653)
Affinity DataKi:  7.20nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440231(CHEMBL2426638)
Affinity DataKi:  7.5nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440218(CHEMBL2426644)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440240(CHEMBL2426647)
Affinity DataKi:  8.10nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440213(CHEMBL2426652)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440234(CHEMBL2426635)
Affinity DataKi:  9.80nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440211(CHEMBL2426654)
Affinity DataKi:  10nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267028(CHEMBL4073525)
Affinity DataKi:  10nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440225(CHEMBL2426625)
Affinity DataKi:  11nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440226(CHEMBL2426643)
Affinity DataKi:  11nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440223(CHEMBL2426627)
Affinity DataKi:  11nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440227(CHEMBL2426642)
Affinity DataKi:  12nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440207(CHEMBL2426633)
Affinity DataKi:  12nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50267031(CHEMBL4079930)
Affinity DataKi:  13nMAssay Description:Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440245(CHEMBL2426659)
Affinity DataKi:  13nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440237(CHEMBL2426631)
Affinity DataKi:  14nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440222(CHEMBL2426628)
Affinity DataKi:  14nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440218(CHEMBL2426644)
Affinity DataKi:  15nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440238(CHEMBL2426630)
Affinity DataKi:  17nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50525764(CHEMBL4515523)
Affinity DataKi:  17nMAssay Description:Inhibition of activated human coagulation factor 11 using pyroGlu-Pro-Arg-pNA as substrate incubated for 10 to 120 mins by spectrofluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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