Affinity DataKi: 3.50E+5nMAssay Description:Inhibition of Monoamine oxidase-B from Bovine liverMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+5nMAssay Description:Inhibition of Monoamine oxidase-B from Bovine liverMore data for this Ligand-Target Pair
Affinity DataKi: 9.40E+5nMAssay Description:Kinetic constant (KI) was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataKi: 1.08E+6nMAssay Description:Kinetic constant was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+6nMAssay Description:Kinetic constant was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+6nMAssay Description:Inhibition of Monoamine oxidase-B from Bovine liverMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+6nMAssay Description:Inhibition of Monoamine oxidase-B from Bovine liverMore data for this Ligand-Target Pair
Affinity DataKi: 4.94E+6nMAssay Description:Kinetic constant was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataKi: 4.94E+6nMAssay Description:Kinetic constant was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataKi: 5.79E+6nMAssay Description:Kinetic constant (KI) was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataKi: 7.10E+6nMAssay Description:Inhibition of Monoamine oxidase-B from Bovine liverMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+7nMAssay Description:Inhibition of Monoamine oxidase-B from Bovine liverMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+7nMAssay Description:Kinetic constant (KI) was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataKi: 1.42E+7nMAssay Description:Kinetic constant (KI) was calculated by inhibition of monoamino oxidase B (MAO B)More data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
TargetNicotinic acetylcholine receptor alpha 5 subunit(Musca domestica)
Gifu University
Curated by ChEMBL
Gifu University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Displacement of [3HIMI from nicotinic acetylcholine receptor in Musca domestica (house fly) head membranes incubated for 60 min by liquid scintillati...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Toray Industries
Curated by ChEMBL
Toray Industries
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human GlyT2 transfected in HEK293 cells assessed as [3H]glycine uptake after 2 hrsMore data for this Ligand-Target Pair