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Found 306 with Last Name = 'niu' and Initial = 'h'
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127441(CHEMBL3628191)
Affinity DataIC50:  3nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127486(CHEMBL3628190)
Affinity DataIC50:  3nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50550025(CHEMBL1923490)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant wild type HIV-1 reverse transcriptase using poly(rA)350/oligo(dT)16 as template/primer preincubated for 1 hr followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127441(CHEMBL3628191)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127486(CHEMBL3628190)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608309(US11691981, Compound 66)
Affinity DataIC50:  4nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127487(CHEMBL3628192)
Affinity DataIC50:  6nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127487(CHEMBL3628192)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50:  7nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)
Affinity DataIC50:  10nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)
Affinity DataIC50:  10nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608284(US11691981, Compound 41)
Affinity DataIC50:  12nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608255(US11691981, Compound 17)
Affinity DataIC50:  12nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  12nMAssay Description:Inhibition of MEK1 in human HT-29 cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608288(US11691981, Compound 45)
Affinity DataIC50:  13nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608308(US11691981, Compound 65)
Affinity DataIC50:  14nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584944(CHEMBL5087319)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608336(US11691981, Compound 73)
Affinity DataIC50:  14nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50550017(CHEMBL4751058)
Affinity DataIC50:  15nMAssay Description:Covalent inhibition of recombinant wild type HIV-1 reverse transcriptase using poly(rA)350/oligo(dT)16 as template/primer preincubated followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584944(CHEMBL5087319)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM50564603(CHEMBL4777294 | US11691981, Compound 77)
Affinity DataIC50:  17nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608337(US11691981, Compound 74)
Affinity DataIC50:  17nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608296(US11691981, Compound 53)
Affinity DataIC50:  18nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608281(US11691981, Compound 38)
Affinity DataIC50:  18nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608271(US11691981, Compound 29)
Affinity DataIC50:  19nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584945(CHEMBL5093862)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584945(CHEMBL5093862)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608300(US11691981, Compound 57)
Affinity DataIC50:  21nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608295(US11691981, Compound 52)
Affinity DataIC50:  21nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608341(US11691981, Compound 78)
Affinity DataIC50:  22nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM50564620(Ly-3200882 | Ly3200882 | US11691981, Compound A)
Affinity DataIC50:  22nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50:  22nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  22nMAssay Description:Inhibition of MEK1 in human LOX cells assessed as inhibition of ERK phosphorylation by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608247(US11691981, Compound 11)
Affinity DataIC50:  24nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50365219(CHEMBL1956073)
Affinity DataIC50:  25nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608314(US11691981, Compound 71)
Affinity DataIC50:  25nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608248(US11691981, Compound 12)
Affinity DataIC50:  28nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608342(US11691981, Compound 79)
Affinity DataIC50:  29nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608305(US11691981, Compound 62)
Affinity DataIC50:  29nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127489(CHEMBL3628194)
Affinity DataIC50:  30nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127488(CHEMBL3628193)
Affinity DataIC50:  30nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608292(US11691981, Compound 49)
Affinity DataIC50:  32nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608302(US11691981, Compound 59)
Affinity DataIC50:  32nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584941(CHEMBL5077167)
Affinity DataIC50:  32nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127488(CHEMBL3628193)
Affinity DataIC50:  32nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127489(CHEMBL3628194)
Affinity DataIC50:  32nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608307(US11691981, Compound 64)
Affinity DataIC50:  32nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Inventisbio

US Patent
LigandPNGBDBM608254(US11691981, Compound 16)
Affinity DataIC50:  34nMAssay Description:TGFβR1 kinase assay was performed according to the instruction manual of the ADP-Glo™ Kinase Assay kit provided by Promega. Prepare 1× Kina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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