Compile Data Set for Download or QSAR
maximum 50k data
Found 48 with Last Name = 'ogbu' and Initial = 'co'
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076227((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0270nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071565(2-(2,2-Diphenyl-ethyl)-7-methyl-1,3-dioxo-2,3,5,8-...)
Affinity DataKi:  0.0350nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076227((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0710nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076224((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0730nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076224((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.0730nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071575(2,2-Dibutyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahydro-...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.230nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071570(8-Isobutyl-2-(4-methoxy-phenyl)-1,3-dioxo-2,3,5,8-...)
Affinity DataKi:  0.280nMAssay Description:Compound was evaluated for its binding affinity to the trypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071573(2-(2,2-Diphenyl-ethyl)-1,3-dioxo-2,3,5,8-tetrahydr...)
Affinity DataKi:  0.300nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076223((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.310nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071571(8-Isobutyl-2-(3-methyl-butyl)-1,3-dioxo-2,3,5,8-te...)
Affinity DataKi:  0.430nMAssay Description:Compound was evaluated for its binding affinity to the trypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076225((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.450nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.640nMAssay Description:Inhibitory concentration of the compound against trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  0.650nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.850nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataKi:  0.850nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071568(2-Amino-2-benzyl-7-methyl-1,3-dioxo-2,3,5,8-tetrah...)
Affinity DataKi:  1.60nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071567(2,2-Dibenzyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahydro...)
Affinity DataKi:  1.90nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076228((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  2.40nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071566(2-Amino-8-benzyl-2-ethyl-1,3-dioxo-2,3,5,8-tetrahy...)
Affinity DataKi:  4.30nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071574(2,2-Diisobutyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahyd...)
Affinity DataKi:  5.10nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50216213(CHEMBL306744)
Affinity DataKi:  5.90nMAssay Description:Compound was evaluated for its binding affinity to the tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071564(2,2-Diallyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahydro-...)
Affinity DataKi:  18nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071572(8-{5-Amino-1-[2-(4-carbamoyl-phenyl)-ethylaminooxa...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for its inhibitory activity against KallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071563(4-(2-{6-amino-2-[7-(3,4-dichlorobenzyl)-13,13-dime...)
Affinity DataKi:  31nMAssay Description:Compound was evaluated for its inhibitory activity against KallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  106nMAssay Description:Compound was evaluated for the inhibition of Tissue type plasminogen activator (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  140nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  165nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  200nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  385nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  508nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  632nMAssay Description:Inhibitory concentration of the compound against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataKi:  699nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  927nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  978nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076226((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076220((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076221((S)-1-((R)-2-Amino-3-phenyl-propionyl)-pyrrolidine...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration of the compound against thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  19.3nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  93nMAssay Description:Inhibitory concentration of the compound against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  251nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration of the compound against coagulation factor VIIaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration of the compound against Coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076219((3S,6R)-6-Amino-6-benzyl-octahydro-indolizine-3-ca...)
Affinity DataIC50:  335nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  415nMAssay Description:Inhibitory concentration of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  495nMAssay Description:Inhibitory concentration of the compound against Tissue type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50076222((1S,7S)-7-Amino-7-benzyl-hexahydro-pyrazolo[1,2-a]...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration of the compound against Urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed