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Found 57 with Last Name = 'ogino' and Initial = 'r'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167871(3-Chloro-4-{4-[5-(4-methyl-pyrimidin-2-yl)-3,4-dih...)
Affinity DataIC50:  0.185nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097342(3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...)
Affinity DataIC50:  0.470nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  0.770nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  0.770nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167872(3-Chloro-4-[4-(4-pyrimidin-2-yl-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  1.38nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  1.59nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167869(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperidin-1-yl)-bu...)
Affinity DataIC50:  5.81nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097345(3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  10nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  11nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011938(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097344(4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-b...)
Affinity DataIC50:  18nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011932(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...)
Affinity DataIC50:  33nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  51nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011934(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...)
Affinity DataIC50:  51nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  51nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011930(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  55nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  55nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  63nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011935(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...)
Affinity DataIC50:  64nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167870(3-Chloro-4-[4-(5-pyrimidin-2-yl-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  79.6nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097342(3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...)
Affinity DataIC50:  84nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011938(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011935(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011930(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011934(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...)
Affinity DataIC50:  160nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011937(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 8-(3...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  199nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  199nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011933(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...)
Affinity DataIC50:  220nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167874(3-Chloro-4-[4-(3-pyrimidin-2-yl-piperidin-1-yl)-bu...)
Affinity DataIC50:  324nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011932(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid ethy...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011934(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid phen...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011933(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 4-ph...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011936(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-py...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity of the compound against 12-lipoxygenase in rat platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167872(3-Chloro-4-[4-(4-pyrimidin-2-yl-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  494nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011938(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-th...)
Affinity DataIC50:  500nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167871(3-Chloro-4-{4-[5-(4-methyl-pyrimidin-2-yl)-3,4-dih...)
Affinity DataIC50:  763nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167870(3-Chloro-4-[4-(5-pyrimidin-2-yl-3,6-dihydro-2H-pyr...)
Affinity DataIC50:  893nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097345(3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011930(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 3-ph...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011935(2-Cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid 2-(2...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167869(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperidin-1-yl)-bu...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against Dopamine receptor D2 in rat striatum membrane using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Daiichi Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50167873(3-Chloro-4-[4-(4-hydroxy-4-pyrimidin-2-yl-piperidi...)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor in rat hippocampus membrane using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Rattus norvegicus)
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50011931((2E)‐3‐phenylprop‐2‐enR...)
Affinity DataIC50:  3.33E+3nMAssay Description:Inhibitory activity of the compound against 15-lipoxygenase in rat polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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