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Found 34 with Last Name = 'oshiro' and Initial = 'g'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317611(4-(3,5-dichloropyridin-4-ylamino)-8-(3-(dimethylam...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317616(4-(3,5-dichloropyridin-4-ylamino)-8-(8-(dimethylam...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317610(9-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-o...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317609(8-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-o...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317615(4-(3,5-dichloropyridin-4-ylamino)-8-(7-(dimethylam...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317614(4-(3,5-dichloropyridin-4-ylamino)-8-(6-(dimethylam...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317604(2-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-o...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317603(8-(cyclopentyloxy)-4-(3,5-dichloropyridin-4-ylamin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005305((SCRIP)3-[2-(2-tert-Butoxycarbonylamino-3-phenyl-p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005305((SCRIP)3-[2-(2-tert-Butoxycarbonylamino-3-phenyl-p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005306(4-Cyclohexyl-2-hydroxy-3-{2-[2-(1-oxo-1,3-dihydro-...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005301(4-Cyclohexyl-2-hydroxy-3-{2-[2-(1-oxo-1,3-dihydro-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317608(7-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-o...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317613(4-(3,5-dichloropyridin-4-ylamino)-8-(5-(dimethylam...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005311(4-Cyclohexyl-2-hydroxy-3-{4-methyl-2-[2-(1-oxo-1,3...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005309(4-Cyclohexyl-2-hydroxy-3-{4-methyl-2-[2-(1-oxo-1,3...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317607(6-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-o...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317612(4-(3,5-dichloropyridin-4-ylamino)-8-(4-(dimethylam...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317606(5-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-o...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005308(4-Cyclohexyl-2-hydroxy-3-{4-methyl-2-[2-(1-oxo-1H,...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005303(4-Cyclohexyl-2-hydroxy-3-{4-methyl-2-[2-(5-oxo-7H-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005302(4-Cyclohexyl-2-hydroxy-3-{4-methyl-2-[2-(3-oxo-tet...)
Affinity DataIC50:  141nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005307(4-Cyclohexyl-2-hydroxy-3-{4-methyl-2-[2-(2-oxo-pyr...)
Affinity DataIC50:  157nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005300(4-Cyclohexyl-2-hydroxy-3-{3-(1H-imidazol-4-yl)-2-[...)
Affinity DataIC50:  186nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005304(4-Cyclohexyl-2-hydroxy-3-{4-methyl-2-[2-(5-oxo-5,7...)
Affinity DataIC50:  207nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50005310(4-Cyclohexyl-3-{2-[2-(1,3-dioxo-1H,3H-benzo[de]iso...)
Affinity DataIC50:  391nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50092350((5-Cyclopentyloxy-6-methoxy-phthalazin-1-yl)-(3,5-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317599(5-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-6-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317605(4-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-o...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317600(8-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-7-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317598(8-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-7-...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317601(3,5-dichloro-N-(7-(cyclopentyloxy)-6-methoxybenzof...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50317602(3,5-dichloro-N-(8-(cyclopentyloxy)-7-methoxychroma...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human His6-tagged PDE4B (152-487) expressed in Escherichia coli BL21 (DE3) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed