Found 239 with Last Name = 'parthasarathy' and Initial = 's' 
Affinity DataIC50: 0.130nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 0.570nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
3D Structure (crystal)TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro binding affinity against cloned human Opioid receptor kappa 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:In vitro binding affinity against cloned human Opioid receptor delta 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant AKT1 expressed in insect cells incubated for 60 mins measured at apparent ATP Km level by kinase ADP-FP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human RSK1 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:In vitro binding affinity against cloned human Opioid receptor kappa 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human p70S6K measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of human PKCbeta2 measured at apparent ATP Km levelMore data for this Ligand-Target Pair
Affinity DataIC50: 38.4nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of AKT1 in human U87MG cells assessed as reduction in GSK3beta Ser9 phosphorylation incubated for 1 hr by alpha screen Surefire assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:In vitro binding affinity against cloned human Opioid receptor delta 1 expressed in HEK 293S cellsMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Tested for effective concentration against cloned human Opioid receptor mu 1More data for this Ligand-Target Pair
