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Found 508 with Last Name = 'peng' and Initial = 'p'
TargetNeuraminidase(Influenza A virus)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50484773(OSELTAMIVIR POTTASIUM CARBOXYLATE | Oseltamivir Po...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Influenza A virus H7N3 N3 neuraminidase expressed in baculovirus using 2'-(4-Methylumbelliferyl)-alpha-D-acetyl neuraminic acid as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50484774(CHEMBL1956716)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Influenza A virus H7N3 N3 neuraminidase expressed in baculovirus using 2'-(4-Methylumbelliferyl)-alpha-D-acetyl neuraminic acid as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-structural protein 1(Influenza A virus (A/turkey/Italy/8000/2002(H7N3)))
Chulalongkorn University

LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  0.120nMpH: 6.5Assay Description:Practically in a microtitre plate, 90 μl of 33 mM MES pH 6.5 containing 4 mM CaCl2 were dispensed in each well, except for the first well of eac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50156468(CHEMBL3792916)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-structural protein 1(Influenza A virus (A/turkey/Italy/8000/2002(H7N3)))
Chulalongkorn University

LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  0.200nMpH: 6.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) determination was carried out by using a 96-well microtitre plate as an array of reaction vessels. In the fir...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of Influenza A virus H7N3 N3 neuraminidase expressed in baculovirus using 2'-(4-Methylumbelliferyl)-alpha-D-acetyl neuraminic acid as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040437(CHEMBL3360608)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040432(CHEMBL3360603)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039330(CHEMBL3355877)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040435(CHEMBL3360606)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040449(CHEMBL3360619)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040448(CHEMBL3360618)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040438(CHEMBL3360609)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039328(CHEMBL3355875)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039334(CHEMBL3355881)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040447(CHEMBL3360617)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039335(CHEMBL3355882)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039329(CHEMBL3355876)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040433(CHEMBL3360604)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039459(CHEMBL3355889)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040441(CHEMBL3360611)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of human recombinant MMP9 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039333(CHEMBL3355880)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040440(CHEMBL3360610)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040436(CHEMBL3360607)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039331(CHEMBL3355878)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040431(CHEMBL3360602)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040450(CHEMBL3352899)
Affinity DataIC50:  0.780nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040451(CHEMBL3360620)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039327(CHEMBL3355874)
Affinity DataIC50:  0.890nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM313972(US10167299, Example 22)
Affinity DataIC50:  1.05nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039332(CHEMBL3355879)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50039460(CHEMBL3355890)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314043(US10167299, Example 157)
Affinity DataIC50:  1.23nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314046(US10167299, Example 160)
Affinity DataIC50:  1.34nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314056(US10167299, Example 170)
Affinity DataIC50:  1.38nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50040434(CHEMBL3360605)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM313989(US10167299, Example 39)
Affinity DataIC50:  1.41nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314054(US10167299, Example 168)
Affinity DataIC50:  1.54nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM313993(US10167299, Example 65)
Affinity DataIC50:  1.62nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314057(US10167299, Example 171)
Affinity DataIC50:  1.64nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314032(US10167299, Example 146)
Affinity DataIC50:  1.75nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314019(US10167299, Example 133)
Affinity DataIC50:  1.79nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM314048(US10167299, Example 162)
Affinity DataIC50:  1.85nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM313955(Compound 3 | US10167299, Example 3)
Affinity DataIC50:  1.95nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM313994(US10167299, Example 66)
Affinity DataIC50:  2.02nMAssay Description:1. HEK293 cells which can stably express CCR5 were inoculated in a 96-well plate and incubated overnight.2. The medium in each well into which cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50161007(CHEMBL3792940)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 60 mins followed by substrate addition b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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