Affinity DataKi: 3.5nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Mixed-type reversible inhibition of bovine acetylcholinesterase using S-acetylthiocholine as substrate incubated for 20 mins prior to substrate addit...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Competitive inhibition of human recombinant MAO-B expressed in supersomes using kynuramine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of bovine AChE at 30 nM using S-acetylthiocholine as as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Mixed type inhibition of electric eel AChE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 93nMAssay Description:Binding affinity to recombinant human MAO-B expressed in Pichia pastoris assessed as inhibition constant using benzylamine as substrate by Michaelis-...More data for this Ligand-Target Pair
Affinity DataKi: 93.4nMAssay Description:Mixed type inhibition of human AChE using acetylthiocholineiodide as substrate measured for every 30 sec for 5 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKi: 98nMAssay Description:Mixed type inhibition of equine serum BChE assessed as Ki using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate additi...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 100nM ΔG°: -40.0kJ/molepH: 7.5 T: 2°CAssay Description:MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Mixed type inhibition of electric eel AChE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Binding affinity to recombinant human MAO-B expressed in Pichia pastoris assessed as inhibition constant using benzylamine as substrate by Michaelis-...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Binding affinity to recombinant human MAO-B expressed in Pichia pastoris assessed as inhibition constant using benzylamine as substrate by Michaelis-...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 400nM ΔG°: -36.5kJ/molepH: 7.5 T: 2°CAssay Description:MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 450nM ΔG°: -36.2kJ/molepH: 7.5 T: 2°CAssay Description:MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ...More data for this Ligand-Target Pair
Affinity DataKi: 1.37E+3nMAssay Description:Mixed-type inhibition of electric eel AChE using S-acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
Affinity DataKi: 1.37E+3nMAssay Description:Mixed-type inhibition of electric eel AChE using S-acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured fo...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Mixed type inhibition of human AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataKi: 4.50E+3nMAssay Description:Tight binding inhibition of recombinant human MAO-B expressed in Pichia pastoris assessed as inhibition constant using benzylamine as substrate at 10...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nM ΔG°: -28.3kJ/molepH: 7.5 T: 2°CAssay Description:MAO A activities were determined spectrophotometrically at 316 nm using kynuramine as substrate. Competitive Ki values were determined by measuring i...More data for this Ligand-Target Pair
Affinity DataKi: 1.57E+4nM ΔG°: -27.4kJ/molepH: 7.5 T: 2°CAssay Description:MAO A activities were determined spectrophotometrically at 316 nm using kynuramine as substrate. Competitive Ki values were determined by measuring i...More data for this Ligand-Target Pair
Affinity DataKi: 3.65E+5nM ΔG°: -19.6kJ/molepH: 7.5 T: 2°CAssay Description:MAO A activities were determined spectrophotometrically at 316 nm using kynuramine as substrate. Competitive Ki values were determined by measuring i...More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant AChE using ATCh as substrate preincubated for 20 mins followed by substrate addition and measured for 3 mins by Ellma...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Universita` Degli Studi Di Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone/11-deoxycorticosteroneMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of bovine AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant MAOA expressed in microsomes of baculovirus-infected insect cell using kynuramine as substrate preincubated for 20 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant MAOA expressed in microsomes of baculovirus-infected insect cell using kynuramine as substrate preincubated for 20 mi...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of MAO-B from Wistar rat brain by radioenzymatic assay in presence of human platelet rich plasmaMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected insect cell microsomes using kynuramine as substrate measured after 30 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of bovine acetylcholinesterase using acetylcholine iodide as substrate incubated for 20 mins prior to substrate addition meausred after 3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human recombinant MAO-A using kynuramine substrate by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZh11B1 cells using [1,2-3H]-11-deoxycorticosterone substrate incubated for 25 mins by HPLC metho...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bari "Aldo Moro
Curated by ChEMBL
University Of Bari "Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human recombinant MAO-B using kynuramine substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universita Degli Studi Di Bari
Curated by ChEMBL
Universita Degli Studi Di Bari
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric methodMore data for this Ligand-Target Pair