Found 128 with Last Name = 'pollastro' and Initial = 'f' TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 99nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 228nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 750nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 760nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 760nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 880nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataKi: 4.75E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor transfected in CHO cells measured for 1.5 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Antagonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as inhibition of 0.25 uM icilin-induced stimulation of intra...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Antagonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 pre-incubated for 10 mins before arachidonic acid substrate addit...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Antagonist activity at recombinant rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium level incubated...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 pre-incubated for 10 mins before arachidonic acid substrate addit...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Antagonist activity at rat recombinant TRPM8 receptor expressed in HEK293 cells assessed as inhibition of 0.25 uM icilin-induced stimulation of intra...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Agonist activity at rat recombinant TRPA1 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 pre-incubated for 10 mins before arachidonic acid substrate addit...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Agonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cells microsomal membranes assessed as reduction in conversion of PGH2 to PGE2 pre-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Agonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as stimulation of intracellular calcium level using Fluo4-AM dy...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at human TRPv1 receptor expressed in HEK293 cells assessed as inhibition of 0.1 um capsaicin-induced stimulation of intracellular...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cells microsomal membranes assessed as reduction in conversion of PGH2 to PGE2 pre-...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 3.27E+3nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 3.46E+3nMAssay Description:Displacement of [3H]-CP-55,940 from human recombinant CB2 receptor expressed in HEK293 cells membrane incubated for 90 minsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Antagonist activity at human TRPv1 receptor expressed in HEK293 cells assessed as inhibition of 0.1 um capsaicin-induced stimulation of intracellular...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing p4xM67-tk-Luc treated 30 mins before TNFalpha challenge measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli MV1190 pre-incubated for 10 mins before arachidonic acid substrate addit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES-1 in interleukin-1 beta-stimulated human A549 cells microsomal membranes assessed as reduction in conversion of PGH2 to PGE2 pre-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human ABHD12 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Universita` Del Piemonte Orientale
Curated by ChEMBL
Universita` Del Piemonte Orientale
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at rat recombinant TRPA1 receptor expressed in HEK293 cells assessed as inhibition of 100 uM allyl isothiocyanate-induced stimula...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human ABHD12 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of IFN gamma-induced STAT3 (unknown origin) activation in HeLa-STAT3-Luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of IFNgamma-induced STAT3 activation in human HeLa cells expressing STAT3 (unknown origin) preincubated for 15 mins followed by IFN-gamma ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.11E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.41E+4nMAssay Description:Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of human ABHD12 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of human ABHD6 transfected in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.63E+4nMAssay Description:Inhibition of FAAH (unknown origin) in human U-937 cells using [ethanolamine-1-3H]AEA as substrate preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
