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Found 45 with Last Name = 'ponte-sucre' and Initial = 'a'
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataKi:  9.80nMAssay Description:Inhibition of human CYP2D6 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50255702(CHEMBL520612 | N-(4'-Methyl phenyl)-6,8-dimethoxy-...)
Affinity DataKi:  28.1nMAssay Description:Inhibition of human CYP2D6 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50255812(CHEMBL481022 | N-(4'-i-Propylphenyl)-6,8-dimethoxy...)
Affinity DataKi:  54.7nMAssay Description:Inhibition of human CYP2D6 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183768((2S,3S)-1-((S)-2-((R)-2-(tert-butoxycarbonyl)-3-ph...)
Affinity DataKi:  100nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183749((2S,3S)-diethyl 1-((S)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  300nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183749((2S,3S)-diethyl 1-((S)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  360nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain in presence of 31.6 uM substrate Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50198075(6,8-dimethoxy-1,3-dimethyl-2-(naphthalen-1-yl)isoq...)
Affinity DataKi:  450nMAssay Description:Inhibition of human CYP2D6 by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183767((2R,3R)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183779((2S,3S)-1-((S)-2-((S)-2-(tert-butoxycarbonyl)-3-ph...)
Affinity DataKi:  500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183754((2S,3S)-dibenzyl 1-((R)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  600nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183742((2R,3R)-diethyl 1-(6-(5-((3aS,4S,6aR)-2-oxo-hexahy...)
Affinity DataKi:  600nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183743((2S,3S)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  600nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183771((2S,3S)-dibenzyl 1-((R)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183766((2S,3S)-dibenzyl 1-((S)-1-(2-(tert-butoxycarbonyl)...)
Affinity DataKi:  700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183765((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183774((2S,3S)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183761((2S,3S)-dibenzyl 1-((R)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183773((2S,3S)-1-((R)-2-((S)-2-(tert-butoxycarbonyl)-3-ph...)
Affinity DataKi:  800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183753((2S,3S)-1-((S)-1-(2-(tert-butoxycarbonyl)acetyl)py...)
Affinity DataKi:  900nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183777((2S,3S)-diethyl 1-((R)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183772((2S,3S)-diethyl 1-((S)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183757((2S,3S)-dibenzyl 1-((S)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183746((2S,3S)-dibenzyl 1-((R)-1-(2-(tert-butoxycarbonyl)...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183745((2S,3S)-dibenzyl 1-((S)-1-(2-(tert-butoxycarbonyl)...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183770((2S,3S)-dibenzyl 1-((R)-2-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183776((2S,3S)-dibenzyl 1-((R)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183763((2S,3S)-diethyl 1-(1-((S)-2-(tert-butoxycarbonyl)-...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183751((2S,3S)-diethyl 1-((S)-1-((R)-2-(tert-butoxycarbon...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183758((2S,3S)-dibenzyl 1-((R)-1-(2-(tert-butoxycarbonyl)...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183778((2S,3S)-dibenzyl 1-((S)-2-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183748((2R,3R)-diethyl 1-((R)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183750((2R,3R)-diethyl 1-((S)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183762((2S,3S)-dibenzyl 1-((S)-1-((S)-2-(tert-butoxycarbo...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183747((2S,3S)-dibenzyl 1-((R)-1-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183780((2R,3R)-diethyl 1-((R)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183764((2S,3S)-dibenzyl 1-((S)-1-(2-(tert-butoxycarbonyl)...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183769((2R,3R)-diethyl 1-((S)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183775((2S,3S)-diethyl 1-((S)-1-((S)-2-(tert-butoxycarbon...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183759((2R,3R)-diethyl 1-(1-((S)-2-(tert-butoxycarbonyl)-...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183744((2S,3S)-dibenzyl 1-((R)-2-((R)-2-(tert-butoxycarbo...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
University Of Wuerzburg

Curated by ChEMBL
LigandPNGBDBM50183760((2S,3S)-1-((R)-2-((R)-2-(tert-butoxycarbonyl)-3-ph...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cell systemMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50255702(CHEMBL520612 | N-(4'-Methyl phenyl)-6,8-dimethoxy-...)
Affinity DataIC50:  56.1nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50255812(CHEMBL481022 | N-(4'-i-Propylphenyl)-6,8-dimethoxy...)
Affinity DataIC50:  109nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50198075(6,8-dimethoxy-1,3-dimethyl-2-(naphthalen-1-yl)isoq...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed