Affinity DataKi: 26nM ΔG°: -44.0kJ/molepH: 7.5 T: 2°CAssay Description:For Ki determinations a matrix of inhibitor and substrate concentrations were tested. Inhibitor concentrations were tested from four times IC50 with ...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Horizon Discovery
Curated by ChEMBL
Horizon Discovery
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Competitive inhibition of Pin1 (unknown origin) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 659nM ΔG°: -35.9kJ/molepH: 7.5 T: 2°CAssay Description:For Ki determinations a matrix of inhibitor and substrate concentrations were tested. Inhibitor concentrations were tested from four times IC50 with ...More data for this Ligand-Target Pair
Affinity DataKi: 8.58E+3nM ΔG°: -29.4kJ/molepH: 7.5 T: 2°CAssay Description:For Ki determinations a matrix of inhibitor and substrate concentrations were tested. Inhibitor concentrations were tested from four times IC50 with ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.580nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.803nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.849nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.852nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.890nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.04nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.07nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.09nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.14nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.21nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.26nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair