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Found 1337 with Last Name = 'rabal' and Initial = 'o'
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420714(CHEMBL2087474)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50388102(CHEMBL2058172)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420730(CHEMBL2087493)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365517(CHEMBL1957508)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365514(CHEMBL1957505)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420719(CHEMBL2087479)
Affinity DataKi:  5.06nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420736(CHEMBL2087483)
Affinity DataKi:  6.20nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365513(CHEMBL1957504)
Affinity DataKi:  6.5nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420719(CHEMBL2087479)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50388102(CHEMBL2058172)
Affinity DataKi:  8nMAssay Description:Inhibition of human PI3Kdelta by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365507(CHEMBL1957498)
Affinity DataKi:  8nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420730(CHEMBL2087493)
Affinity DataKi:  9.80nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420703(CHEMBL2087492)
Affinity DataKi:  10.1nMAssay Description:Inhibition of human PI3Kalpha (p110alpha/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420714(CHEMBL2087474)
Affinity DataKi:  14.2nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420736(CHEMBL2087483)
Affinity DataKi:  14.7nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420703(CHEMBL2087492)
Affinity DataKi:  15.6nMAssay Description:Inhibition of human PI3Kdelta (p110delta/p85alpha) by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365511(CHEMBL1957502)
Affinity DataKi:  17.1nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420719(CHEMBL2087479)
Affinity DataKi:  26.7nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365506(CHEMBL1957497)
Affinity DataKi:  29nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365508(CHEMBL1957499)
Affinity DataKi:  43nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365514(CHEMBL1957505)
Affinity DataKi:  44nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420703(CHEMBL2087492)
Affinity DataKi:  59.8nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365517(CHEMBL1957508)
Affinity DataKi:  60nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50388102(CHEMBL2058172)
Affinity DataKi:  62.9nMAssay Description:Inhibition of PI3Kgamma assessed as accumulation of ADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365509(CHEMBL1957500)
Affinity DataKi:  65nMAssay Description:Inhibition of human PI3K p110delta/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365513(CHEMBL1957504)
Affinity DataKi:  65nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420730(CHEMBL2087493)
Affinity DataKi:  84nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365507(CHEMBL1957498)
Affinity DataKi:  86nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50388102(CHEMBL2058172)
Affinity DataKi:  94.1nMAssay Description:Inhibition of human PI3Kbeta by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365511(CHEMBL1957502)
Affinity DataKi:  102nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420736(CHEMBL2087483)
Affinity DataKi:  124nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50420714(CHEMBL2087474)
Affinity DataKi:  179nMAssay Description:Inhibition of human PI3Kgamma by ADP accumulation based HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365506(CHEMBL1957497)
Affinity DataKi:  181nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365509(CHEMBL1957500)
Affinity DataKi:  210nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365508(CHEMBL1957499)
Affinity DataKi:  410nMAssay Description:Inhibition of human PI3K p110alpha/p85alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365513(CHEMBL1957504)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365506(CHEMBL1957497)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365514(CHEMBL1957505)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365517(CHEMBL1957508)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365508(CHEMBL1957499)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365509(CHEMBL1957500)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365511(CHEMBL1957502)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50365507(CHEMBL1957498)
Affinity DataKi: >500nMAssay Description:Inhibition of human PI3K p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of full length recombinant human HDAC1 expressed in baculovirus infected Sf9 cells using RHKK-Ac as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of recombinant full length C-terminal FLAG His-tagged human HDAC1 expressed in baculovirus infected Sf21 insect cells using RHK-K(Ac)-AMC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196772(CHEMBL3936651)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of recombinant N-terminal GST tagged PDE6C (unknown origin) expressed in baculovirus infected Sf9 cells using cGMP as substrate by malachi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of recombinant full length C-terminal GST fusion-tagged human HDAC2 expressed in baculovirus infected insect cells using RHK-K(Ac)-AMC as ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of full length recombinant human HDAC2 expressed in baculovirus infected Sf9 cells using RHKK-Ac as substrate by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM50388111(CHEMBL2058163)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PI3Kalpha assessed as accumulation of ADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
University Of Navarra

Curated by ChEMBL
LigandPNGBDBM50196760(CHEMBL3954968)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected Sf9 cells using cGMP as substrate after 30...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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