Compile Data Set for Download or QSAR
maximum 50k data
Found 300 with Last Name = 'radesca' and Initial = 'l'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000066((2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-eth...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000068(CHEMBL142700 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50037480((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)
Affinity DataKi:  0.290nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000776(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperaz...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000078((3,4-Dichloro-benzyl)-methyl-(2-pyrrolidin-1-yl-et...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000773(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000773(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007314(CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...)
Affinity DataKi:  0.490nMAssay Description:Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000065(CHEMBL141501 | [2-(3,4-Dichloro-phenyl)-ethyl]-eth...)
Affinity DataKi:  0.510nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000769(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(5-fluoro-pent...)
Affinity DataKi:  0.520nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000067(CHEMBL347514 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000070(CHEMBL143178 | N-[2-(3,4-Dichloro-phenyl)-ethyl]-N...)
Affinity DataKi:  0.730nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000080(CHEMBL422834 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000074(CHEMBL142596 | [2-(3-Chloro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000769(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(5-fluoro-pent...)
Affinity DataKi:  0.860nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000079(CHEMBL142755 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000774(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-iodo-propyl...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007316((3,4-Dichloro-benzyl)-methyl-(2-pyrrolidin-1-yl-cy...)
Affinity DataKi:  1.20nMAssay Description:Compound was tested for the inhibitory activity against Sigma opioid receptor by using [3H]-(+)-3-PPP as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000771(CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethy...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000771(CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethy...)
Affinity DataKi:  1.23nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000774(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-iodo-propyl...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003743((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  1.30nMAssay Description:Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000071(CHEMBL143360 | N-[2-(3,4-Dichloro-phenyl)-ethyl]-N...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003753(6,7-Dichloro-2-(2-pyrrolidin-1-yl-ethyl)-1,2,3,4-t...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003743((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  1.30nMAssay Description:Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000073(Allyl-[2-(3,4-dichloro-phenyl)-ethyl]-(2-pyrrolidi...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000076(CHEMBL141945 | [2-(3,4-Dichloro-phenyl)-ethyl]-pro...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000085(CHEMBL142297 | N*1*-[2-(3,4-Dichloro-phenyl)-ethyl...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003748(CHEMBL342223 | [2-(3,4-Dichloro-phenyl)-ethyl]-(1-...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000081(CHEMBL358109 | [2-(4-Chloro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003754((-)-1-[2-(3,4-Dichloro-phenyl)-ethyl]-2-pyrrolidin...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000083(CHEMBL142336 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003743((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  2nMAssay Description:Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000082(CHEMBL142353 | Methyl-(2-naphthalen-2-yl-ethyl)-(2...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003750(CHEMBL137348 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007312(CHEMBL320828 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...)
Affinity DataKi:  2.40nMAssay Description:Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003752(1-[2-(3,4-Dichloro-phenyl)-ethyl]-3-pyrrolidin-1-y...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007315(CHEMBL103065 | [2-(3,4-Dichloro-phenyl)-ethyl]-eth...)
Affinity DataKi:  3.10nMAssay Description:Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50007313(CHEMBL102695 | [2-(3,4-Dichloro-phenyl)-ethyl]-eth...)
Affinity DataKi:  3.5nMAssay Description:Compound was tested for the inhibitory activity against Sigma opioid receptor by using [3H]-(+)-3-PPP as radioligand in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003745(1-[2-(3,4-Dichloro-phenyl)-ethyl]-3-pyrrolidin-1-y...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003744(CHEMBL342942 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000772(CHEMBL70861 | [2-(3,4-Dichloro-phenyl)-ethyl]-(3-f...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000772(CHEMBL70861 | [2-(3,4-Dichloro-phenyl)-ethyl]-(3-f...)
Affinity DataKi:  4.22nMAssay Description:Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003756((+)-1-[2-(3,4-Dichloro-phenyl)-ethyl]-2-pyrrolidin...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000086(CHEMBL142406 | N-[2-(3,4-Dichloro-phenyl)-ethyl]-N...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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