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Found 16 with Last Name = 'rawat' and Initial = 'ak'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM11162((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)
Affinity DataIC50:  18nMAssay Description:DPP-IV inhibitory activity was determined by measuring the p-nitroaniline (pNA) released from the chromogenic substrate hydrolysis (H-Gly-Pro-pNA). T...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM152800(1-(2-(4-(7-Chloro-4-quinolyl)piperazin-1-yl)acetyl...)
Affinity DataIC50:  3.73E+3nMAssay Description:DPP-IV inhibitory activity was determined by measuring the p-nitroaniline (pNA) released from the chromogenic substrate hydrolysis (H-Gly-Pro-pNA). T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM152801(4-(2-(4-(7-Chloro-4-quinolyl)piperazin-1-yl)acetyl...)
Affinity DataIC50:  5.96E+3nMAssay Description:DPP-IV inhibitory activity was determined by measuring the p-nitroaniline (pNA) released from the chromogenic substrate hydrolysis (H-Gly-Pro-pNA). T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM152799(1-(2-(4-(3-chlorophenyl)piperazin-1-yl)acetyl)pipe...)
Affinity DataIC50:  6.06E+3nMAssay Description:DPP-IV inhibitory activity was determined by measuring the p-nitroaniline (pNA) released from the chromogenic substrate hydrolysis (H-Gly-Pro-pNA). T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM152798(3-(2-(4-(2-Pyridyl)piperazin-1-yl)acetyl)thiazolid...)
Affinity DataIC50:  6.08E+3nMAssay Description:DPP-IV inhibitory activity was determined by measuring the p-nitroaniline (pNA) released from the chromogenic substrate hydrolysis (H-Gly-Pro-pNA). T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50443464(CHEMBL259888)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of recombinant human PTP1B by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50443463(CHEMBL406596)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of recombinant human PTP1B by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50443461(CHEMBL3087456)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of recombinant human PTP1B by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50443460(CHEMBL3087457)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of recombinant human PTP1B by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50443462(CHEMBL3087455)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of recombinant human PTP1B by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
School Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50443465(CHEMBL3087459)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of recombinant human PTP1B by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM50340427(1-((3S,8S,9S,10R,13S,14S,17R)-16-(benzylamino)-3-h...)
Affinity DataIC50:  2.13E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM50340428(3-(3,4-dimethoxyphenyl)-1-((3S,8R,9S,10R,13S,14S)-...)
Affinity DataIC50:  2.62E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM50340430((2S,4aR,4bS,6aS,9R,11aS,11bS)-2-Hydroxy-9-(4-isopr...)
Affinity DataIC50:  2.91E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM50340429((2S,4aR,4bS,6aS,9R,11aS,11bS)-2-Hydroxy-9-(4-metho...)
Affinity DataIC50:  3.27E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Csir-Central Drug Research Institute

LigandPNGBDBM50340426(16-Dehydropregnenolone acetate | CHEMBL1761683)
Affinity DataIC50:  3.56E+4nMAssay Description:Inhibition of human DPP-4 assessed as cleavage of substrate using H-Gly-Pro-AMC chromogenic substrate after 10 mins by double beam spectrophotometerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed