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Found 48 with Last Name = 'ren' and Initial = 'hy'
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)

Curated by ChEMBL
LigandPNGBDBM50343621(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-nitrobenzyl)pi...)
Affinity DataKi:  0.430nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)

Curated by ChEMBL
LigandPNGBDBM50343619(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-bromobenzyl)pi...)
Affinity DataKi:  0.780nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)

Curated by ChEMBL
LigandPNGBDBM50343620(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-iodobenzyl)pip...)
Affinity DataKi:  0.800nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)

Curated by ChEMBL
LigandPNGBDBM50343618(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-fluorobenzyl)p...)
Affinity DataKi:  0.850nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)

Curated by ChEMBL
LigandPNGBDBM50343622(1-(1,3-Benzodioxol-5-ylmethyl)-4-(4-methylbenzyl)-...)
Affinity DataKi:  0.910nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat brain membranes by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Homo sapiens (Human))
Key Laboratory Of Radiopharmaceuticals (Beijing Normal University)

Curated by ChEMBL
LigandPNGBDBM50338990(1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to emopamil binding proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  0.420nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataIC50:  13.9nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381227(CHEMBL484378)
Affinity DataIC50:  45nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381225(CHEMBL483373)
Affinity DataIC50:  78nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50305644((2E,4E)-5-Benzo[1,3]dioxol-5-yl-penta-2,4-dienoic ...)
Affinity DataIC50:  230nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50148573((E,E)-1-piperoylpiperidine | 1-[(2E,4E)-5-(1,3-ben...)
Affinity DataIC50:  260nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381231(CHEMBL2018556)
Affinity DataIC50:  330nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381228(CHEMBL450300)
Affinity DataIC50:  330nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50148573((E,E)-1-piperoylpiperidine | 1-[(2E,4E)-5-(1,3-ben...)
Affinity DataIC50:  404nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381230(CHEMBL2018555)
Affinity DataIC50:  750nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  800nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381229(CHEMBL120544)
Affinity DataIC50:  960nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381239(CHEMBL2018562)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381230(CHEMBL2018555)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381224(CHEMBL2018554)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381236(CHEMBL457218)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381238(CHEMBL2018561)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381233(CHEMBL332479)
Affinity DataIC50:  1.97E+3nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381229(CHEMBL120544)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50305644((2E,4E)-5-Benzo[1,3]dioxol-5-yl-penta-2,4-dienoic ...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381238(CHEMBL2018561)
Affinity DataIC50:  3.17E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381235(CHEMBL2018559)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381227(CHEMBL484378)
Affinity DataIC50:  3.66E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381225(CHEMBL483373)
Affinity DataIC50:  3.82E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381236(CHEMBL457218)
Affinity DataIC50:  5.21E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381239(CHEMBL2018562)
Affinity DataIC50:  5.57E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381231(CHEMBL2018556)
Affinity DataIC50:  7.55E+3nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381226(PIPERIC ACID)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381235(CHEMBL2018559)
Affinity DataIC50:  1.61E+4nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381226(PIPERIC ACID)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381234(CHEMBL2018558)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381233(CHEMBL332479)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381237(CHEMBL2018560)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381232(CHEMBL2018557)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381228(CHEMBL450300)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50128111(1-((2E,4E)-5-Benzo[1,3]dioxol-5-yl-penta-2,4-dieny...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381234(CHEMBL2018558)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381232(CHEMBL2018557)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50381237(CHEMBL2018560)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM50128111(1-((2E,4E)-5-Benzo[1,3]dioxol-5-yl-penta-2,4-dieny...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-B in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
General Hospital Of Pla

Curated by ChEMBL
LigandPNGBDBM15579(CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MAO-A in Sprague-Dawley rat brain homogenate using kynuramine as substrate preincubated for 10 mins measured by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed