Found 618 with Last Name = 'reyna' and Initial = 'n' TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant human MTH1 assessed as hydrolysis of dGTP to dGMP and pyrophosphate after 15 mins by malachite green-based microplate reade...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.810nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.870nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.930nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.970nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.51nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.51nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.54nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.56nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.57nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.58nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Md Anderson Cancer Center
Curated by ChEMBL
Md Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant MTH1 (unknown origin) assessed as hydrolysis of 8-oxodGTP to 8-oxodGMP and pyrophosphate by PPiLight assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.82nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 1.92nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in mouse Panc02 cells assessed as reduction in NFK level incubated for 48 hrs by RFMS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
Affinity DataIC50: 2.02nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
